Post-selection inference in regression models for group testing data

被引:0
|
作者
Shen, Qinyan [1 ]
Gregory, Karl [1 ]
Huang, Xianzheng [1 ]
机构
[1] Univ South Carolina, Dept Stat, 219 LeConte,1523 Greene St, Columbia, SC 29208 USA
关键词
confidence intervals; EM algorithm; individual testing; LASSO; variable selection; VALID CONFIDENCE-INTERVALS;
D O I
10.1093/biomtc/ujae101
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We develop a methodology for valid inference after variable selection in logistic regression when the responses are partially observed, that is, when one observes a set of error-prone testing outcomes instead of the true values of the responses. Aiming at selecting important covariates while accounting for missing information in the response data, we apply the expectation-maximization algorithm to compute maximum likelihood estimators subject to LASSO penalization. Subsequent to variable selection, we make inferences on the selected covariate effects by extending post-selection inference methodology based on the polyhedral lemma. Empirical evidence from our extensive simulation study suggests that our post-selection inference results are more reliable than those from naive inference methods that use the same data to perform variable selection and inference without adjusting for variable selection.
引用
收藏
页数:12
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