COMBINED EFFECT OF OBETICHOLIC ACID AND BEZAFIBRATE IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS AND INADEQUATE RESPONSE TO OR INTOLERANCE OF URSODEOXYCHOLIC ACID: RESULTS FROM TWO PHASE 2 CLINICAL TRIALS

被引：0
|
作者：
Levy, Cynthia [1 ]
Hejda, Vaclav [2 ]
Louvet, Alexandre [3 ]
Younes, Ziad [4 ]
Mendizabal, Manuel [5 ]
Bonder, Alan [6 ]
Zou, Heng [7 ]
Civitarese, Antonio [7 ]
Villamil, Alejandra [8 ]
Nevens, Frederik [9 ]
机构：
[1] Univ Miami, Sch Med, Coral Gables, FL 33124 USA
[2] Univ Hosp Plzen, Plzen, Czech Republic
[3] Univ Hosp Lille, Lille, France
[4] Gastro One, Germantown, TN USA
[5] Hosp Univ Austral, Pilar, Argentina
[6] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[7] Intercept Pharmaceut Inc, Morristown, NJ USA
[8] Hosp Italiano Buenos Aires, Hepat Autoimmun Unit, Buenos Aires, DF, Argentina
[9] Univ Hosp KU Leuven, Leuven, Belgium
来源：
HEPATOLOGY | 2024年 / 79卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
5019-C
引用
收藏
页码：E52 / E52
页数：1
相关论文
共 50 条
  • [31] EFFECT OF FIBRATE-ADD-ON TREATMENT IN PRIMARY BILIARY CHOLANGITIS PATIENTS WITH AN INSUFFICIENT RESPONSE TO URSODEOXYCHOLIC ACID
    Freissmuth, C.
    Kozbial, K.
    Staettermayer, A. F.
    Beinhardt, S.
    Stern, R.
    Halilbasic, E.
    Ferenci, P.
    Trauner, M.
    Hofer, H.
    JOURNAL OF HEPATOLOGY, 2016, 64 : S434 - S435
  • [32] Worse Response to Ursodeoxycholic Acid in Primary Biliary Cholangitis Patients with Autoimmune Hepatitis Features
    Wen, Maoyao
    Men, Ruoting
    Fan, Xiaoli
    Shen, Yi
    Ni, Ping
    Hu, Zhichao
    Yang, Li
    DIGESTIVE DISEASES, 2021, 39 (04) : 366 - 374
  • [33] ECONOMIC IMPACT OF NON-RESPONSE TO URSODEOXYCHOLIC ACID IN PRIMARY BILIARY CHOLANGITIS PATIENTS
    Sharma, Parivrudh
    Crighton, Lynne
    Vijayan, Balasubramaniam
    English, Shirley
    Mukhopadhya, Ashis
    GUT, 2019, 68 : A129 - A130
  • [34] Analysis of predictive response scores to treatment with ursodeoxycholic acid in patients with primary biliary cholangitis
    Brunet, Eduard
    Hernandez, Leticia
    Miquel, Mireia
    Sanchez-Delgado, Jordi
    Dalmau, Blai
    Valero, Oliver
    Vergara, Mercedes
    Casas, Meritxell
    MEDICINA CLINICA, 2019, 152 (10): : 377 - 383
  • [35] EARLY IDENTIFICATION OF INSUFFICIENT BIOCHEMICAL RESPONSE TO URSODEOXYCHOLIC ACID IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS
    Perez, Carla Fiorella Murillo
    Ioannou, Stephanie
    Hassanally, Iman
    Trivedi, Palak
    Corpechot, Christophe
    Van der Meer, Adriaan J.
    Lammers, Willem J.
    Battezzati, Pier Maria
    Lindor, Keith D.
    Nevens, Frederik
    Kowdley, Kris
    Bruns, Tony
    Cazzagon, Nora
    Floreani, Annarosa
    Mason, Andrew L.
    Gulamhusein, Aliya F.
    Ponsioen, Cyriel
    Carbone, Marco
    Lleo, Ana
    Mayo, Marlyn J.
    Dalekos, George
    Gatselis, Nikolaos K.
    Thorburn, Douglas
    Verhelst, Xavier
    Pares, Albert
    Janssen, Harry L. A.
    Invernizzi, Pietro
    Vuppalanchi, Raj
    Hirschfield, Gideon
    Hansen, Bettina E.
    Levy, Cynthia
    HEPATOLOGY, 2021, 74 : 759A - 760A
  • [36] A validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis
    Yagi, Minami
    Matsumoto, Kosuke
    Komori, Atsumasa
    Abe, Masanori
    Hashimoto, Naoaki
    Inao, Mie
    Namisaki, Tadashi
    Kawata, Kazuhito
    Ninomiya, Masashi
    Fujii, Hideki
    Takahashi, Atsushi
    Kang, Jong-Hon
    Takamura, Masaaki
    Arakawa, Mie
    Joshita, Satoru
    Sato, Ken
    Itakura, Jun
    Nomura, Takako
    Kakisaka, Keisuke
    Kaneko, Akira
    Tamura, Yamato
    Miura, Ryo
    Aiso, Mitsuhiko
    Arizumi, Toshihiko
    Asaoka, Yoshinari
    Kikuchi, Kentaro
    Takikawa, Yasuhiro
    Masaki, Tsutomu
    Umemura, Takeji
    Honda, Akira
    Ohira, Hiromasa
    Kawada, Norifumi
    Yoshiji, Hitoshi
    Mochida, Satoshi
    Takikawa, Hajime
    Tanaka, Atsushi
    LIVER INTERNATIONAL, 2020, 40 (08) : 1926 - 1933
  • [37] Obeticholic acid for the treatment of primary biliary cholangitis in adult patients: clinical utility and patient selection
    Bowlus, Christopher L.
    HEPATIC MEDICINE-EVIDENCE AND RESEARCH, 2016, 8 : 89 - 95
  • [38] Effect of obeticholic acid treatment in patients with primary biliary cholangitis on categorical shifts in GLOBE score
    Harms, M. H.
    Lammers, W. J.
    Hansen, B. E.
    Mayo, M.
    Pares, A.
    Malecha, E. S.
    Pencek, R.
    MacConell, L.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S106 - S106
  • [39] Effect of Obeticholic Acid Treatment in Patients With Primary Biliary Cholangitis on Categorical Shifts in GLOBE Score
    Harms, Maren H.
    Lammers, Willem J.
    Hansen, Bettina E.
    Mayo, Marlyn J.
    Pares, Albert
    Malecha, Elizabeth Smoot
    Pencek, Richard
    MacConell, Leigh
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2017, 112 : S495 - S495
  • [40] Additive improvement induced by bezafibrate in patients with primary biliary cirrhosis showing refractory response to ursodeoxycholic acid
    Takeuchi, Yasuto
    Ikeda, Fusao
    Fujioka, Shin-ichi
    Takaki, Toshiyuki
    Osawa, Toshiya
    Yasunaka, Tetsuya
    Miyake, Yasuhiro
    Takaki, Akinobu
    Iwasaki, Yoshiaki
    Kobashi, Haruhiko
    Yamamoto, Kazuhide
    Itoshima, Tatsuya
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2011, 26 (09) : 1395 - 1401
12345