Comprehensive Collection of Whole-Slide Images and Genomic Profiles for Patients with Bladder Cancer

被引:0
|
作者
Xu, Pei-Hang [1 ,2 ]
Li, Tianqi [2 ,3 ,4 ]
Qu, Fengmei [5 ]
Tian, Mingkang [5 ]
Wang, Jun [6 ,7 ,8 ]
Gan, Hualei [2 ,3 ,4 ]
Ye, Dingwei [1 ,2 ]
Ren, Fei [9 ]
Shen, Yijun [1 ,2 ]
机构
[1] Fudan Univ, Dept Urol, Shanghai Canc Ctr, Shanghai, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China
[3] Fudan Univ, Shanghai Canc Ctr, Dept Pathol, Shanghai, Peoples R China
[4] Fudan Univ, Inst Pathol, Shanghai 200032, Peoples R China
[5] Jinfeng Lab, Chongqing 401329, Peoples R China
[6] Sun Yat Sen Univ, Canc Ctr, Dept Urol, Guangzhou, Peoples R China
[7] State Key Lab Oncol Southern China, Guangzhou, Peoples R China
[8] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, Canc Ctr, Guangzhou, Peoples R China
[9] Chinese Acad Sci, Inst Comp Technol, State Key Lab Processors, Beijing 100190, Peoples R China
关键词
ALIGNMENT;
D O I
10.1038/s41597-024-03526-3
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Bladder cancer is one of the leading causes of cancer-related mortality in the urinary system. Understanding genomic information is important in the treatment and prognosis of bladder cancer, but the current method used to identify mutations is time-consuming and labor-intensive. There are now many novel and convenient ways to predict cancerous genomics from pathological slides. However, the publicly available datasets are limited, especially for Asian populations. In this study, we developed a dataset consisting of 75 Asian cases of bladder cancers and 112 Whole-Slide Images with one to two images obtained for each patient. This dataset provides information on the most frequently and clinically significant mutated genes derived by whole-exome sequencing in these patients. This dataset will facilitate exploration and development of novel diagnostic and therapeutic technologies for bladder cancer.
引用
收藏
页数:8
相关论文
共 50 条
  • [31] An automatic entropy method to efficiently mask histology whole-slide images
    Yipei Song
    Francesco Cisternino
    Joost M. Mekke
    Gert J. de Borst
    Dominique P. V. de Kleijn
    Gerard Pasterkamp
    Aryan Vink
    Craig A. Glastonbury
    Sander W. van der Laan
    Clint L. Miller
    Scientific Reports, 13
  • [32] COMPARISON OF DIFFERENT METHODS FOR TISSUE SEGMENTATION IN HISTOPATHOLOGICAL WHOLE-SLIDE IMAGES
    Bandi, Peter
    van de Loo, Rob
    Intezar, Milad
    Geijs, Daan
    Ciompi, Francesco
    van Ginneken, Bram
    van der Laak, Jeroen
    Litjens, Geert
    2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017), 2017, : 591 - 595
  • [33] A Feature Learning Framework for Reproducible Invasive Tumor Detection of Breast Cancer in Whole-Slide Images
    Cruz-Roa, Angel
    Basavanhally, Ajay
    Gonzalez, Fabio
    Feldman, Michael
    Ganesan, Shridar
    Shih, Natalie
    Tomaszewski, John
    Gilmore, Hannah
    Madabhushi, Anant
    MODERN PATHOLOGY, 2015, 28 : 40A - 40A
  • [34] An automatic entropy method to efficiently mask histology whole-slide images
    Song, Yipei
    Cisternino, Francesco
    Mekke, Joost M. M.
    de Borst, Gert J. J.
    de Kleijn, Dominique P. V.
    Pasterkamp, Gerard
    Vink, Aryan
    Glastonbury, Craig A. A.
    van der Laan, Sander W. W.
    Miller, Clint L. L.
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [35] Whole-Slide Images Versus Glass Slides for Pathology Resident Education
    Fox, Sharon
    Vander Heide, Richard
    Law, C.
    Faulkner-Jones, Beverly
    MODERN PATHOLOGY, 2015, 28 : 129A - 129A
  • [36] Automated histological classification of whole-slide images of gastric biopsy specimens
    Yoshida, Hiroshi
    Shimazu, Taichi
    Kiyuna, Tomoharu
    Marugame, Atsushi
    Yamashita, Yoshiko
    Cosatto, Eric
    Taniguchi, Hirokazu
    Sekine, Shigeki
    Ochiai, Atsushi
    GASTRIC CANCER, 2018, 21 (02) : 249 - 257
  • [37] Segmentation of Overlapped Steatosis in Whole-Slide Liver Histopathology Microscopy Images
    Roy, Mousumi
    Wang, Fusheng
    Teodoro, George
    Vos, Miriam B.
    Farris, Alton Brad
    Kong, Jun
    2018 40TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2018, : 810 - 813
  • [38] Automated histological classification of whole-slide images of gastric biopsy specimens
    Hiroshi Yoshida
    Taichi Shimazu
    Tomoharu Kiyuna
    Atsushi Marugame
    Yoshiko Yamashita
    Eric Cosatto
    Hirokazu Taniguchi
    Shigeki Sekine
    Atsushi Ochiai
    Gastric Cancer, 2018, 21 : 249 - 257
  • [39] SGCL: Spatial guided contrastive learning on whole-slide pathological images
    Lin, Tiancheng
    Yu, Zhimiao
    Xu, Zengchao
    Hu, Hongyu
    Xu, Yi
    Chen, Chang-Wen
    MEDICAL IMAGE ANALYSIS, 2023, 89
  • [40] A Validated Neuroanatomical Segmentation Protocol for the Hippocampal Subfields in Whole-slide Images
    Karlovich, Esma
    Insausti, Ricardo
    Marx, Gabriel
    Dangoor, Diana
    Krassner, Maggie
    Farinas, Marissa
    Farrell, Kurt
    Crary, John
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021, 80 (06): : 580 - 580