Synthesis of acridones via Ir(<sc>iii</sc>)-catalyzed amination annulation of oxazoles with anthranils

被引：0

作者：

Zhou, Han-Yi ^{[1
,2
]}

Dong, Lin ^{[1
,2
]}

机构：

[1] Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Sichuan Engn Lab Plant Sourced Drug, Educ Minist & Sichuan Prov, Chengdu 610041, Peoples R China

[2] Sichuan Univ, Sichuan Res Ctr Drug Precis Ind Technol, West China Sch Pharm, Chengdu 610041, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 20期

关键词：

METAL-FREE SYNTHESIS; BOND-CLEAVAGE; FUNCTIONALIZATION; CHALLENGES; DESIGN;

D O I：

10.1039/d4ob00377b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An unprecedented Ir(iii)-catalyzed C-H activation/amination/annulation of 2-phenyloxazoles with anthranils for the highly selective preparation of acridone derivatives in one-pot under controlled conditions is reported. This protocol is characterized by atom economy and high regioselectivity. A wide range of anthranils with 2-phenyloxazoles were well tolerated and afforded the desired products in moderate to good yields, in which the anthranil serves as a convenient amination reagent.

引用

页码：4036 / 4040

页数：5

共 50 条

[41] Direct synthesis of gold(<sc>iii</sc>)-annulated perylene diimides via multiple C-H aurations
Chen, Wei
Yang, Qing-Yu
Wu, Kongchuan
Lin, Jianbin
Zhang, Hui-Jun
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (16): : 4496 - 4501
[42] Synthesis, characterization and in vitro cytotoxicity of gallium(<sc>iii</sc>)-dithiocarbamate complexes
Salvarese, Nicola
Morellato, Nicolo
Gobbi, Carolina
Gandin, Valentina
De Franco, Michele
Marzano, Cristina
Dolmella, Alessandro
Bolzati, Cristina
DALTON TRANSACTIONS, 2024, 53 (10) : 4526 - 4543
[43] Manganese(<sc>iii</sc>) acetate in organic synthesis: a review of the past decade
Wang, Jian
Zhang, Yan
Zhou, Ying
Gu, Xin
Han, Bingxu
Ding, Xuelu
Liang, Shuai
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (23): : 6850 - 6917
[44] A Mn(<sc>iii</sc>)-catalyzed arylboronic acid-based cascade reaction via a nonclassical organometallic-radical mechanism
Qian, Hui-Min
Zhang, Jian-Dong
Ji, Shun-Jun
Xu, Xiao-Ping
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (10) : 2739 - 2746
[45] Experimental and computational kinetic evaluations of silver(<sc>i</sc>)-catalyzed oxidation of p-chlorophenol by hexacyanoferrate(<sc>iii</sc>): exploring the mechanistic pathway
Rolaniya, Asha
Yadav, Akta
Jain, Priyanka
Sailani, Riya
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2025, 27 (04) : 2023 - 2032
[46] The role of ancillary ligands on benzodipyridophenazine-based Ru(<sc>ii</sc>)/Ir(<sc>iii</sc>) complexes in dark and light toxicity against TNBC cells
Nivedya, T.
Das, Rishav
Kumar, Selva R.
Shanavas, Shanooja
Rangaswamy, Bhaskar
Aatif, Mujthaba A.
Mukherjee, Chandrapaul
Roy, Riona
Sengupta, Jhimli
Bose, Bipasha
Kumar, Ashok S. K.
Paira, Priyankar
DALTON TRANSACTIONS, 2025,
[47] Synthesis of 3,4-unsubstituted isoquinolone derivatives from benzimidates and vinylene carbonate via cobalt(<sc>iii</sc>)-catalyzed C-H activation/cyclization
Xu, Weiyan
Dang, Haowen
Sheng, Huiru
Shen, Jiabin
Wang, Min
ORGANIC & BIOMOLECULAR CHEMISTRY, 2025,
[48] Synthesis of gem-difluorinated pentacyclic indenopyrazolopyrazolones via Rh(<sc>iii</sc>)-catalyzed cascade C-H functionalization/[3+2] dipolar cycloaddition
Liu, Fu-Xiaomin
Chen, Weijie
Cai, Ying
Zhou, Zhi
Yi, Wei
Cheng, Kui
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (09) : 2512 - 2517
[49] Zinc tetrafluoroborate catalyzed α-stereoselective synthesis of pseudoglycals: efficient synthesis of digitoxin α-<sc>l</sc>-amicetose
Bharali, Mrinmoy Manash
Santra, Abhishek
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 22 (40) : 8114 - 8118
[50] Palladium(<sc>ii</sc>)-catalyzed intramolecular C-H amination to carbazole: the crucial role of cyclic diacyl peroxides
Yuan, Ting
Fu, Kang
Shi, Lei
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (16): : 4529 - 4538

← 1 2 3 4 5 →