Horner-Wadsworth-Emmons olefination for bioconjugation

被引：0

作者：

Aye, Yimon ^{[1
]}

机构：

[1] Swiss Fed Inst Technol Lausanne EPFL, Lausanne, Switzerland

来源：

NATURE SYNTHESIS | 2024年 / 3卷 / 08期

关键词：

D O I：

10.1038/s44160-024-00571-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Through site-specific generation of intermediary reactive aldehydes, Horner-Wadsworth-Emmons olefination can now deliver selective functionalization of stable recombinant proteins and monoclonal antibodies, whilst preserving protein integrity.

引用

页码：935 / 936

页数：2

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