Mutations in the splicing factor SF3B1 are linked to frequent emergence of HLA-DRlow/neg monocytes in lower-risk myelodysplastic neoplasms

被引：0

作者：

Winter, Susann ^{[1
]}

Schneider, Marie ^{[2
]}

Oelschlaegel, Uta ^{[1
]}

Maggioni, Giulia ^{[3
,4
]}

Riva, Elena ^{[3
,4
]}

Raddi, Marco Gabriele ^{[5
]}

Bencini, Sara ^{[6
]}

Peruzzi, Benedetta ^{[6
]}

Choy, Desmond ^{[3
]}

Antunes Dos Reis, Rita ^{[3
]}

Guese, Esther ^{[7
,8
]}

Lischer, Christopher ^{[7
,8
]}

Vera, Julio ^{[7
,8
]}

Timms, Jessica A. ^{[3
]}

Sompairac, Nicolas ^{[3
]}

Sockel, Katja ^{[1
]}

Poloni, Antonella ^{[9
]}

Tunger, Antje ^{[10
,11
,12
,13
,14
,15
]}

Della Porta, Matteo Giovanni ^{[4
,16
]}

Santini, Valeria ^{[5
]}

Schmitz, Marc ^{[10
,11
,12
,13
,14
,15
,17
,18
]}

Platzbecker, Uwe ^{[2
,17
,18
,19
]}

Kordasti, Shahram ^{[3
,9
,20
]}

机构：

[1] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Fac Med Carl Gustav Carus, Dept Internal Med 1, Dresden, Germany

[2] Univ Leipzig Med Ctr, Dept Hematol Cellular Therapy & Hemostaseol & Inf, Leipzig, Germany

[3] Kings Coll London, Comprehens Canc Ctr, Sch Canc & Pharmaceut Sci, London, England

[4] IRCCS Humanitas Res Hosp, Milan, Italy

[5] Univ Florence, AOU Careggi Dept Expt & Clin Med, MDS Unit, Hematol, Florence, Italy

[6] AOU Careggi, Flow Cytometry Diagnost Ctr & Immunotherapy CDCI, Florence, Italy

[7] Friedrich Alexander Univ Erlangen Nurnberg, Lab Syst Tumor Immunol, Univ klinikum Erlangen, Erlangen, Germany

[8] Comprehens Canc Ctr Erlangen EMN, Deutsch Zent Immuntherapie, Erlangen, Germany

[9] Univ Politecn Marche, Dept Clin & Mol Sci, Ancona, Italy

[10] Tech Univ Dresden, Inst Immunol, Fac Med Carl Gustav Carus, Dresden, Germany

[11] Natl Ctr Tumor Dis NCT, Dresden, Germany

[12] Tech Univ Dresden, German Canc Res Ctr DKFZ, Dresden, Germany

[13] Tech Univ Dresden, Fac Med, Dresden, Germany

[14] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dresden, Germany

[15] Helmholtz Zentrum Dresden Rossendorf HZDR, Dresden, Germany

[16] Humanitas Univ, Dept Biomed Sci, Milan, Italy

[17] German Canc Consortium DKTK, Partner Site Dresden, Heidelberg, Germany

[18] German Canc Res Ctr, Heidelberg, Germany

[19] German MDS Study Grp D MDS, Leipzig, Germany

[20] Guys Hosp, Haematol Dept, London, England

来源：

LEUKEMIA | 2024年 / 38卷 / 06期

关键词：

IMMUNOSUPPRESSIVE THERAPY; MDS;

D O I：

10.1038/s41375-024-02249-z

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1427 / 1431

页数：5

共 35 条

[11] CANCER-LINKED SF3B1 MUTATIONS CAUSE FAULTY SPLICING AND SUGP1 BINDING
不详
CANCER DISCOVERY, 2019, 9 (10) : 1336 - 1336
[12] Splicing factor 3B subunit 1 (SF3B1) mutation in the context of therapy-related myelodysplastic syndromes
Volpe, Virginia O.
Al Ali, Najla
Chan, Onyee
Padron, Eric
Sallman, David A.
Kuykendall, Andrew
Sweet, Kendra
Lancet, Jeffrey E.
Komrokji, Rami S.
BRITISH JOURNAL OF HAEMATOLOGY, 2022, 198 (04) : 713 - 720
[13] Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts
Valeria Visconte
Ali Tabarroki
Li Zhang
Yvonne Parker
Edy Hasrouni
Reda Mahfouz
Kyoichi Isono
Haruhiko Koseki
Mikkael A Sekeres
Yogen Saunthararajah
John Barnard
Daniel Lindner
Heesun J Rogers
Ramon V Tiu
Journal of Hematology & Oncology, 7
[14] Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts
Visconte, Valeria
Tabarroki, Ali
Zhang, Li
Parker, Yvonne
Hasrouni, Edy
Mahfouz, Reda
Isono, Kyoichi
Koseki, Haruhiko
Sekeres, Mikkael A.
Saunthararajah, Yogen
Barnard, John
Lindner, Daniel
Rogers, Heesun J.
Tiu, Ramon V.
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
[15] Clinical significance of SF3B1 mutations in Korean patients with myelodysplastic syndromes and myelodysplasia/myeloproliferative neoplasms with ring sideroblasts
Seo, Ja Young
Lee, Ki-O
Kim, Sun-Hee
Kim, Kihyun
Jung, Chul Won
Jang, Jun Ho
Kim, Hee-Jin
ANNALS OF HEMATOLOGY, 2014, 93 (04) : 603 - 608
[16] Clinical significance of SF3B1 mutations in Korean patients with myelodysplastic syndromes and myelodysplasia/myeloproliferative neoplasms with ring sideroblasts
Ja Young Seo
Ki-O Lee
Sun-Hee Kim
Kihyun Kim
Chul Won Jung
Jun Ho Jang
Hee-Jin Kim
Annals of Hematology, 2014, 93 : 603 - 608
[17] SPLICING ALTERATIONS IN LOW RISK MYELODYSPLASTIC SYNDROME, TGF-B PATHWAY DEREGULATION IN SF3B1 MUTATED PATIENTS
Hajrullaj, H.
Onorato, A.
Valenzuela, M.
Cristiano, A.
Silvestrini, G.
Pieraccioli, M.
Galossi, E.
Falconi, G.
Hutter, S.
Nadarajah, N.
Latagliata, R.
Haferlach, T.
Bielli, P.
Voso, M. T.
Fabiani, E.
HAEMATOLOGICA, 2024, 109 : 23 - 24
[18] Mutations of the SF3B1 splicing Factor in Chronic Lymphocytic Leukemia: Association with Progression and Fludarabine-Refractoriness
Rossi, Davide
Bruscaggin, Alessi
Spina, Valeria
Rasi, Silvia
Khiabanian, Hossein
Messina, Monica
Fangazio, Marco
Vaisitti, Tiziana
Guarini, Anna
Del Giudice, Ilaria
Cerri, Michaela
Cresta, Stefania
Deambrogi, Clara
Gargiulo, Ernesto
Gattei, Valter
Forconi, Francesco
Bertoni, Francesco
Deaglio, Silvia
Rabadan, Raul
Pasqualucci, Laura
Foa, Robin
Dalla-Favera, Riccardo
Gaidano, Gianluca
BLOOD, 2011, 118 (21) : 215 - 215
[19] Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
Rossi, Davide
Bruscaggin, Alessio
Spina, Valeria
Rasi, Silvia
Khiabanian, Hossein
Messina, Monica
Fangazio, Marco
Vaisitti, Tiziana
Monti, Sara
Chiaretti, Sabina
Guarini, Anna
Del Giudice, Ilaria
Cerri, Michaela
Cresta, Stefania
Deambrogi, Clara
Gargiulo, Ernesto
Gattei, Valter
Forconi, Francesco
Bertoni, Francesco
Deaglio, Silvia
Rabadan, Raul
Pasqualucci, Laura
Foa, Robin
Dalla-Favera, Riccardo
Gaidano, Gianluca
BLOOD, 2011, 118 (26) : 6904 - 6908
[20] Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
Víctor Quesada
Laura Conde
Neus Villamor
Gonzalo R Ordóñez
Pedro Jares
Laia Bassaganyas
Andrew J Ramsay
Sílvia Beà
Magda Pinyol
Alejandra Martínez-Trillos
Mónica López-Guerra
Dolors Colomer
Alba Navarro
Tycho Baumann
Marta Aymerich
María Rozman
Julio Delgado
Eva Giné
Jesús M Hernández
Marcos González-Díaz
Diana A Puente
Gloria Velasco
José M P Freije
José M C Tubío
Romina Royo
Josep L Gelpí
Modesto Orozco
David G Pisano
Jorge Zamora
Miguel Vázquez
Alfonso Valencia
Heinz Himmelbauer
Mónica Bayés
Simon Heath
Marta Gut
Ivo Gut
Xavier Estivill
Armando López-Guillermo
Xose S Puente
Elías Campo
Carlos López-Otín
Nature Genetics, 2012, 44 : 47 - 52

← 1 2 3 4 →