SPLICING ALTERATIONS IN LOW RISK MYELODYSPLASTIC SYNDROME, TGF-B PATHWAY DEREGULATION IN SF3B1 MUTATED PATIENTS

被引:0
|
作者
Hajrullaj, H. [1 ]
Onorato, A. [1 ]
Valenzuela, M. [1 ]
Cristiano, A. [1 ]
Silvestrini, G. [1 ]
Pieraccioli, M. [2 ]
Galossi, E. [1 ]
Falconi, G. [1 ]
Hutter, S. [3 ]
Nadarajah, N. [3 ]
Latagliata, R. [4 ,5 ]
Haferlach, T. [3 ]
Bielli, P. [1 ]
Voso, M. T. [1 ]
Fabiani, E. [1 ,6 ]
机构
[1] Univ Tor Vergata, Dept Biomed & Prevent, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Milan, Italy
[3] MLL Munich Leukemia Lab, Munich, Germany
[4] Sapienza Univ, Unita Operat Complessa UOC Ematol, Osped Belcolle, Rome, Italy
[5] Sapienza Univ, Div Cellular Biotechnol & Hematol, Rome, Italy
[6] UniCamillus St Camillus Int Univ Hlth Sci, Rome, Italy
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
C20
引用
收藏
页码:23 / 24
页数:2
相关论文
共 50 条
  • [1] DEREGULATION OF THE TRANSFORMING GROWTH FACTOR-B PATHWAY IN LOW-RISK MDS PATIENTS SF3B1 MUTATED
    Cristiano, A.
    Silvestrini, G.
    Hajrullaj, H.
    Galossi, E.
    Falconi, G.
    Palmieri, R.
    Hutter, S.
    Nadarajah, N.
    Gumenyuk, S.
    Buccisano, F.
    Fenu, S.
    Latagliata, R.
    Haferlach, T.
    Voso, M. T.
    Fabiani, E.
    HAEMATOLOGICA, 2022, 107 : 13 - 14
  • [2] The molecular and therapeutic relevance of SF3B1 in myelodysplastic syndrome
    Lappin, K. M.
    Liberante, F. G.
    Savage, K. I.
    Mills, K. I.
    BRITISH JOURNAL OF HAEMATOLOGY, 2015, 169 : 87 - 87
  • [3] ABERRANT SPLICING DURING ERYTHROID DIFFERENTIATION IN SF3B1 MUTATED SIDEROBLASTIC
    Conte, S.
    Vesterlund, L.
    Katayama, S.
    Karimi, M.
    Unneberg, P.
    Papaemmanuil, E.
    Jansson, M.
    Mortera-Blanco, T.
    Dimitriou, M.
    Sander, B.
    Skoog, T.
    Campbells, P.
    Kere, J.
    Hellstrom-Lindberg, E.
    HAEMATOLOGICA, 2013, 98 : 73 - 74
  • [4] Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1
    Ambaglio, Ilaria
    Malcovati, Luca
    Papaemmanuil, Elli
    Laarakkers, Coby M.
    Della Porta, Matteo G.
    Galli, Anna
    Da Via, Matteo C.
    Bono, Elisa
    Ubezio, Marta
    Travaglino, Erica
    Albertini, Riccardo
    Campbell, Peter J.
    Swinkels, Dorine W.
    Cazzola, Mario
    HAEMATOLOGICA, 2013, 98 (03) : 420 - 423
  • [5] Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts
    Valeria Visconte
    Ali Tabarroki
    Li Zhang
    Yvonne Parker
    Edy Hasrouni
    Reda Mahfouz
    Kyoichi Isono
    Haruhiko Koseki
    Mikkael A Sekeres
    Yogen Saunthararajah
    John Barnard
    Daniel Lindner
    Heesun J Rogers
    Ramon V Tiu
    Journal of Hematology & Oncology, 7
  • [6] Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts
    Visconte, Valeria
    Tabarroki, Ali
    Zhang, Li
    Parker, Yvonne
    Hasrouni, Edy
    Mahfouz, Reda
    Isono, Kyoichi
    Koseki, Haruhiko
    Sekeres, Mikkael A.
    Saunthararajah, Yogen
    Barnard, John
    Lindner, Daniel
    Rogers, Heesun J.
    Tiu, Ramon V.
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
  • [7] A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation
    Ma, Liya
    Liang, Bin
    Hu, Huixian
    Yang, Wenli
    Lin, Shengyun
    Cao, Lihong
    Li, Kongfei
    Kuang, Yuemin
    Shou, Lihong
    Jin, Weimei
    Lan, Jianping
    Ye, Xingnong
    Le, Jing
    Lei, Huyi
    Fu, Jiaping
    Lin, Ying
    Jiang, Wenhua
    Zheng, Zhiying
    Jiang, Songfu
    Fu, Lijuan
    Su, Chuanyong
    Yin, XiuFeng
    Liu, Lixia
    Qin, Jiayue
    Jin, Jie
    Qian, Shenxian
    Ouyang, Guifang
    Tong, Hongyan
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [8] The Significance of Variant Allele Frequency in SF3B1 Mutated Myelodysplastic Neoplasms/Syndromes
    Lachowiez, Curtis A.
    Asimomitis, Georgios
    Bernard, Elsa
    Tang, Ivory
    Creignou, Maria
    Germing, Ulrich
    Gattermann, Norbert
    Malcovati, Luca
    Cazzola, Mario
    Lindberg, Eva Hellstrom
    Papaemmanuil, Elli
    Loghavi, Sanam
    BLOOD, 2023, 142
  • [9] A Murine Model Harboring Cooperating DNMT3A and SF3B1 Mutations Phenocopies SF3B1 Driven Myelodysplastic Syndrome
    Wallace, Lashanale
    Leal-Cervantes, Ana
    Metidji, Amina
    Myers, Jacquelyn
    Rolle, Chandra
    Tillman, Heather
    Obeng, Esther A.
    BLOOD, 2022, 140 : 5862 - 5863
  • [10] SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts
    V Visconte
    H Makishima
    A Jankowska
    H Szpurka
    F Traina
    A Jerez
    C O'Keefe
    H J Rogers
    M A Sekeres
    J P Maciejewski
    R V Tiu
    Leukemia, 2012, 26 : 542 - 545