PROGESTERONE AND ESTRADIOL INCREASE CYTOSOLIC CA2+ IN SINGLE-RAT HEPATOCYTES

被引：32

作者：

SANCHEZBUENO, A ^{[1
]}

SANCHO, MJ ^{[1
]}

COBBOLD, PH ^{[1
]}

机构：

[1] UNIV BASQUE COUNTRY,FAC SCI,DEPT BIOCHEM,E-48080 BILBAO,SPAIN

来源：

BIOCHEMICAL JOURNAL | 1991年 / 280卷

基金：

英国惠康基金;

关键词：

D O I：

10.1042/bj2800273

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Progesterone (300-400-mu-M) and oestradiol (25-200-mu-M) induce a prompt rise in the cytosolic free Ca2+ concentration (free Ca) in single rat hepatocytes, but testosterone, cortisol and dexamethasone do not. These increases are dependent on the presence of extracellular Ca2+. Both progesterone and oestradiol block phenylephrine-induced free Ca oscillations. These data suggest a certain specificity of the response of free Ca to steroids and may explain some of the non-genomic effects of these steroids on hepatocytes.

引用

页码：273 / 276

页数：4

共 50 条

[31] CHRONIC-RENAL-FAILURE INCREASES CYTOSOLIC CA2+ OF HEPATOCYTES
KLIN, M
SMOGORZEWSKI, M
MASSRY, SG
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1995, 269 (01): : G103 - G109
[32] EFFECTS OF HG2+ ON CYTOSOLIC CA2+ IN ISOLATED SKATE HEPATOCYTES
NATHANSON, MH
MARIWALLA, K
BALLATORI, N
BOYER, JL
CELL CALCIUM, 1995, 18 (05) : 429 - 439
[33] Serotonin-stimulated increase in cytosolic Ca2+ in cultured rat heart endothelial cells
Lee, HZ
Wu, CH
EUROPEAN JOURNAL OF PHARMACOLOGY, 1999, 384 (01) : 53 - 60
[34] Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: properties of the Ca2+ influx channel
Lenz, T
Kleineke, JW
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1997, 273 (05): : C1526 - C1532
[35] CHOLESTATIC BILE-ACIDS INCREASE CYTOSOLIC CA++ ACTIVITY IN RAT HEPATOCYTES
ANWER, MS
ENGELKING, LR
NOLAN, K
ZIMNIAK, P
LESTER, R
GASTROENTEROLOGY, 1987, 92 (05) : 1716 - 1716
[36] Regulation of the cytosolic Ca2+ concentration by Ca2+ stores in single smooth muscle cells from rat cerebral arteries
Kamishima, T
McCarron, JG
JOURNAL OF PHYSIOLOGY-LONDON, 1997, 501 (03): : 497 - 508
[37] INTRINSIC CYTOSOLIC CALCIUM BUFFERING IN SINGLE-RAT CARDIAC MYOCYTES
BERLIN, JR
BASSANI, JWM
BERS, DM
BIOPHYSICAL JOURNAL, 1994, 66 (02) : A92 - A92
[38] Extracellular Ca2+ increases cytosolic free Ca2+ in freshly isolated rat odontoblasts
Guo, L
Davidson, RM
JOURNAL OF BONE AND MINERAL RESEARCH, 1999, 14 (08) : 1357 - 1366
[39] Depolarization-evoked increase of cytosolic Ca2+:: A new fluorescent assay in rat cortical neurons
Francisconi, S.
Salvati, P.
Caccia, C.
FEBS JOURNAL, 2007, 274 : 272 - 272
[40] AGGREGATION FAILS TO INCREASE CYTOSOLIC [CA2+](CA2+](I)) IN AEQUORIN-LOADED HUMAN PLATELETS
ORCHARD, MA
SCRUTTON, MC
THROMBOSIS AND HAEMOSTASIS, 1993, 69 (06) : 1159 - 1159

← 1 2 3 4 5 →