Transcriptional regulation by promoters with enhancer function

被引：37

作者：

Dao, Lan T. M. ^{[1
]}

Spicuglia, Salvatore ^{[2
,3
]}

机构：

[1] Vinmec Res Inst Stem Cell & Gene Technol VRISG, Hanoi, Vietnam

[2] Aix Marseille Univ, INSERM, TAGC, UMR, Marseille, France

[3] Equipe Labellisee Ligue Canc, Paris, France

来源：

TRANSCRIPTION-AUSTIN | 2018年 / 9卷 / 05期

关键词：

Enhancer; promoter; Epromoter; gene regulation; reporter-assay; CRISPR/Cas9;

D O I：

10.1080/21541264.2018.1486150

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Promoters with enhancer activity have been described recently. In this point of view, we will discuss current findings highlighting the commonality of this type of regulatory elements, their genetic and epigenetic characteristics, their potential biological roles in the regulation of gene expression and the underlining molecular mechanisms.

引用

页码：307 / 314

页数：8

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