DISSOLUTION SYSTEM FOR NIFEDIPINE SUSTAINED-RELEASE FORMULATIONS

被引：11
|
作者：
CHAUDHARY, RS
GANGWAL, SS
GUPTA, VK
SHAH, YN
JINDAL, KC
KHANNA, S
机构：
[1] Lupin Laboratories Limited, MIDC, Chikalthana, Aurangabad
来源：
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1994年 / 20卷 / 07期
关键词：
D O I：
10.3109/03639049409038366
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
An in-vitro system for evaluating Nifedipine sustained release formulations has been developed. Two systems were evaluated to simulate sink conditions and correlate the system with flow through dissolution system in mechanism. For the purpose of evaluation two commercial brands were studied. The acidic biphasic system was found to be good for in-vitro dissolution rate evaluation of sustained release nifedipine tablets. It can be successfully utilized for routine quality control work.
引用
收藏
页码：1267 / 1274
页数：8
相关论文
共 50 条
  • [41] SUSTAINED-RELEASE NATURAL-RUBBER FORMULATIONS FOR UREA
    BARY, EMA
    ELSHEKEIL, AG
    HELALY, FM
    SARHAN, AA
    RAZIK, HHA
    [J]. PLASTICS RUBBER AND COMPOSITES PROCESSING AND APPLICATIONS, 1992, 17 (02): : 99 - 107
  • [42] THE BIOAVAILABILITY OF SUSTAINED-RELEASE NICOTINIC-ACID FORMULATIONS
    NEUVONEN, PJ
    ROIVAS, L
    LAINE, K
    SUNDHOLM, O
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1991, 32 (04) : 473 - 476
  • [43] Determination of the behavior of sustained-release pharmaceuticals using a tablet-dissolution system
    Senger, AR
    [J]. NACHRICHTEN AUS CHEMIE TECHNIK UND LABORATORIUM, 1997, 45 (03): : A2 - A3
  • [44] SCIENTIFIC RATIONALE AND CLINICAL IMPLICATIONS OF SUSTAINED-RELEASE FORMULATIONS
    KELLAWAY, IW
    [J]. BRITISH JOURNAL OF CLINICAL PRACTICE, 1988, 42 (04): : 9 - 13
  • [45] Effect of food on the comparative bioavailability of two commercially available sustained-release tablet formulations containing nifedipine.
    Qato, MK
    Naddaf, AR
    Mohammed, FA
    [J]. FASEB JOURNAL, 1999, 13 (05): : A809 - A809
  • [46] PREPARATION AND DISSOLUTION CHARACTERISTICS OF INDOMETHACIN SUSTAINED-RELEASE BEADS
    KURUMADDALI, KR
    BETAGERI, GV
    RAVIS, WR
    [J]. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1992, 18 (15) : 1709 - 1717
  • [47] RELEASE CHARACTERISTICS OF NIFEDIPINE SUSTAINED-RELEASE GRANULES INVITRO AND IN HEALTHY-SUBJECTS
    KOHRI, N
    MIYAZAKI, K
    ARITA, T
    SHIMONO, H
    NOMURA, A
    YASUDA, H
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1987, 35 (06) : 2504 - 2509
  • [48] RELATIVE BIOAVAILABILITY OF IMMEDIATE-RELEASE AND SUSTAINED-RELEASE HYDRALAZINE FORMULATIONS
    LUDDEN, TM
    ROTENBERG, KS
    LUDDEN, LK
    SHEPHERD, AMM
    WOODWORTH, JR
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1988, 77 (12) : 1026 - 1032
  • [49] INVIVO EVALUATION OF RAPID RELEASE AND SUSTAINED-RELEASE GELUCIRE CAPSULE FORMULATIONS
    DENNIS, AB
    FARR, SJ
    KELLAWAY, IW
    TAYLOR, G
    DAVIDSON, R
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1990, 65 (1-2) : 85 - 100
  • [50] Influence of dissolution medium agitation on release profiles of sustained-release tablets
    Costa, P
    Lobo, JMS
    [J]. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2001, 27 (08) : 811 - 817
12345