METHYL 6-[(4-BROMOBENZOYLOXY)(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHYL)-METHYL]-2-NAPHTHALENECARBOXYLATE

被引：2

作者：

GAO, Q

YU, KL

MANSURI, MM

KERNS, EH

STARRETT, JE

机构：

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1995年 / 51卷

关键词：

D O I：

10.1107/S0108270195001958

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The structure of the title compound, C34H33BrO4, determined using direct methods and refined including the anomalous scattering from the Br atoms, shows that the absolute configuration at the C14 atom is R. High displacement parameters of several C atoms indicate conformational disorder of the saturated ring in the tetramethyltetrahydronaphthyl group. The packing of the molecules is stabilized by van der Waal's forces.

引用

页码：1672 / 1675

页数：4

共 50 条

[21] Synthesis of the trifluoromethylated retinoial aromatic amide - 4-[1-(5,6,7,8-tetrahydro-3-trifluoromethyl-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid
Qing, FL
Fan, JF
JOURNAL OF FLUORINE CHEMISTRY, 1999, 96 (02) : 159 - 161
[22] Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN)
Heck, Michael C.
Wagner, Carl E.
Shahani, Pritika H.
MacNeill, Maid
Grozic, Aleksandra
Darwaiz, Tamana
Shimabuku, Micah
Deans, David G.
Robinson, Nathan M.
Salama, Samer H.
Ziller, Joseph W.
Ma, Ning
van der Vaart, Arjan
Marshall, Pamela A.
Jurutka, Peter W.
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (19) : 8924 - 8940
[23] AROMATIC RETINOIDS .2. A SHORT AND CONVENIENT ROUTE TO 5-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-ANTHRACENYL)-2-FURAN AND 2-THIOPHENE CARBOXYLIC-ACIDS
EUSTACHE, J
BERNARDON, JM
SHROOT, B
TETRAHEDRON LETTERS, 1988, 29 (35) : 4409 - 4410
[24] Studies on the metabolism and disposition of the new retinoid 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl] benzoic acid .4. Absorption, metabolism, excretion and plasma protein binding in various animals and man
Mizojiri, K
Okabe, H
Sugeno, K
Misaki, A
Ito, M
Kominami, G
Esumi, Y
Takaichi, M
Harada, T
Seki, H
Inaba, A
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1997, 47 (03): : 259 - 269
[25] Development of Selective TGR5 Ligands Based on the 5,6,7,8-Tetrahydro-5,5,8,8-tetramethylnaphthalene Skeleton
Terui, Ryusei
Yanase, Yuta
Yokoo, Hidetomo
Suhara, Yoshitomo
Makishima, Makoto
Demizu, Yosuke
Misawa, Takashi
CHEMMEDCHEM, 2021, 16 (03) : 458 - 462
[26] BIOTRANSFORMATION OF A NEW SYNTHETIC RETINOID, 4-[(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHYL)CARBAMOYL] BENZOIC-ACID (AM-80), IN THE RAT - STRUCTURE ELUCIDATION OF THE METABOLITES BY MASS AND NMR SPECTROMETRY
HASHIMOTO, S
MIZOBUCHI, M
KURODA, T
OKABE, H
MIZOJIRI, K
TAKAHASHI, S
KIKUCHI, J
TERUI, Y
XENOBIOTICA, 1994, 24 (12) : 1177 - 1193
[27] NOTES ON THE SYNTHESIS OF SULFONATED DERIVATIVES OF 5,6,7,8-TETRAHYDRO-1-NAPHTHYLAMINE AND 5,6,7,8-TETRAHYDRO-2-NAPHTHYLAMINE
COURTIN, A
HELVETICA CHIMICA ACTA, 1981, 64 (02) : 572 - 578
[28] THE EPITHELIAL DIFFERENTIATING ACTIVITY INVIVO OF (E)-4-[2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHYLENYL)-1-PROPENYL]BENZOIC ACID AND 4,4-DIFLUORORETINOIC ACID
MILLER, DA
STEPHENSJARNAGIN, A
DELUCA, HF
BIOCHEMICAL JOURNAL, 1985, 227 (01) : 311 - 316
[29] Combined high-performance liquid chromatography and radioimmunoassay for a novel retinobenzoic acid derivative, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-carbamoyl] benzoic acid (Am-80), in human plasma
Itoh, M
Misaki, A
Kominami, G
ANALYTICAL LETTERS, 1996, 29 (08) : 1377 - 1388
[30] SYNTHESES AND BIOLOGICAL UTILITY OF ISOTOPICALLY LABELED 4-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHYL)ETHENYL)BENZOIC ACID (LGD1069)
ZHANG, L
BADEA, BA
ENYEART, D
BERGER, EM
MAIS, DE
BOEHM, MF
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 51 - MEDI

← 1 2 3 4 5 →