STATIC AND SCANNING ARRAY DETECTION IN CAPILLARY ELECTROPHORESIS MASS-SPECTROMETRY

被引：25
|
作者：
REINHOUD, NJ
SCHRODER, E
TJADEN, UR
NIESSEN, WMA
DEBRAUW, MCT
VANDERGREEF, J
机构：
[1] CTR BIOPHARMACEUT SCI, DIV ANALYT CHEM, POB 9502, 2300 RA LEIDEN, NETHERLANDS
[2] FINNIGAN MAT GMBH, W-2800 BREMEN 14, GERMANY
[3] TNO, CIVO INST, INSTRUMENTAL ANAL SECT, 3700 AJ ZEIST, NETHERLANDS
来源：
JOURNAL OF CHROMATOGRAPHY | 1990年 / 516卷 / 01期
关键词：
D O I：
10.1016/S0021-9673(01)90212-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
An array detection system based on position- and time-resolved ion counting was evaluated for capillary electrophoresis-mass spectrometry using continuous-flow fast atom bombardment and a liquid-junction coupling. Peptides with molecular masses up to 3200 were measured. A 100-1000-fold improvement over conventional detection was demonstrated by applying the array detector in scanning and static modes. Absolute detection limits in the range 1-5 fmol are achievable. © 1990.
引用
收藏
页码：147 / 155
页数：9
相关论文
共 50 条
  • [21] Simultaneous determination of the main metabolites in rice leaves using capillary electrophoresis mass spectrometry and capillary electrophoresis diode array detection
    Sato, S
    Soga, T
    Nishioka, T
    Tomita, M
    PLANT JOURNAL, 2004, 40 (01): : 151 - 163
  • [22] NEW DEVELOPMENTS IN MICROSCALE SEPARATIONS AND MASS-SPECTROMETRY FOR BIOMONITORING - CAPILLARY ELECTROPHORESIS AND ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY
    SMITH, RD
    WAHL, JH
    LIGHTWAHL, KJ
    WINGER, BE
    JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH, 1993, 40 (2-3): : 147 - 158
  • [23] STRUCTURAL CHARACTERIZATION OF LIPOPOLYSACCHARIDES FROM PSEUDOMONAS AS AERUGINOSA USING CAPILLARY ELECTROPHORESIS MASS-SPECTROMETRY AND TANDEM MASS-SPECTROMETRY
    AURIOLA, S
    THIBAULT, P
    ALTMAN, E
    SADOVSKAYA, I
    MASOUD, H
    RICHARDS, JC
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 114 - ANYL
  • [24] OPTIMIZATION OF CAPILLARY ZONE ELECTROPHORESIS ELECTROSPRAY IONIZATION PARAMETERS FOR THE MASS-SPECTROMETRY AND TANDEM MASS-SPECTROMETRY ANALYSIS OF PEPTIDES
    MOSELEY, MA
    JORGENSON, JW
    SHABANOWITZ, J
    HUNT, DF
    TOMER, KB
    JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1992, 3 (04) : 289 - 300
  • [25] ONLINE ISOTACHOPHORETIC ANALYTE FOCUSING FOR IMPROVEMENT OF DETECTION LIMITS IN CAPILLARY ELECTROPHORESIS ELECTROSPRAY MASS-SPECTROMETRY
    TINKE, AP
    REINHOUD, NJ
    NIESSEN, WMA
    TJADEN, UR
    VANDERGREEF, J
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1992, 6 (09) : 560 - 563
  • [26] INFLUENCE OF CAPILLARY DIMENSIONS ON THE PERFORMANCE OF A COAXIAL CAPILLARY ELECTROPHORESIS ELECTROSPRAY MASS-SPECTROMETRY INTERFACE
    TETLER, LW
    COOPER, PA
    POWELL, B
    JOURNAL OF CHROMATOGRAPHY A, 1995, 700 (1-2) : 21 - 26
  • [27] DETERMINATION OF ISOFLAVONES USING CAPILLARY ELECTROPHORESIS IN COMBINATION WITH ELECTROSPRAY MASS-SPECTROMETRY
    ARAMENDIA, MA
    GARCIA, I
    LAFONT, F
    MARINAS, JM
    JOURNAL OF CHROMATOGRAPHY A, 1995, 707 (02) : 327 - 333
  • [28] DETERMINATION OF BIOACTIVE PEPTIDES USING CAPILLARY ZONE ELECTROPHORESIS MASS-SPECTROMETRY
    MOSELEY, MA
    DETERDING, LJ
    TOMER, KB
    JORGENSON, JW
    ANALYTICAL CHEMISTRY, 1991, 63 (02) : 109 - 114
  • [29] IMPROVED ELECTROSPRAY IONIZATION INTERFACE FOR CAPILLARY ZONE ELECTROPHORESIS - MASS-SPECTROMETRY
    SMITH, RD
    BARINAGA, CJ
    UDSETH, HR
    ANALYTICAL CHEMISTRY, 1988, 60 (18) : 1948 - 1952
  • [30] ONLINE CAPILLARY ELECTROPHORESIS ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY OF NUCLEOTIDES
    ZHAO, ZX
    WAHL, JH
    UDSETH, HR
    HOFSTADLER, SA
    FUCIARELLI, AF
    SMITH, RD
    ELECTROPHORESIS, 1995, 16 (03) : 389 - 395
12345