IDENTIFICATION OF HUMAN GENES INVOLVED IN REPAIR AND TOLERANCE OF DNA DAMAGE

被引：6
|
作者：
KAINA, B
FRITZ, G
COQUERELLE, T
机构：
[1] Kernforschungszentrum Karlsruhe, Institut für Genetik und für Toxikologie, Karlsruhe, W-7500
来源：
RADIATION AND ENVIRONMENTAL BIOPHYSICS | 1991年 / 30卷 / 01期
关键词：
D O I：
10.1007/BF01595570
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
An overview is presented on strategies of cloning mammalian DNA repair genes. Complementation of human and rodent repair defects and mutagen hypersensitivities by chromosome and DNA mediated gene transfer and mRNA microinjection is described, and the features of the cloned human DNA repair genes are summarized. It is shown that transfection of repair deficient cell lines with cloned bacterial and human genes may give rise to protection from the genotoxic effects of mutagens. © 1991 Springer-Verlag.
引用
收藏
页码：1 / 19
页数：19
相关论文
共 50 条
  • [31] Human DNA repair genes, 2005
    Wood, RD
    Mitchell, M
    Lindahl, T
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2005, 577 (1-2) : 275 - 283
  • [32] Identification and Validation of a Novel DNA Damage and DNA Repair Related Genes Based Signature for Colon Cancer Prognosis
    Wang, Xue-quan
    Xu, Shi-wen
    Wang, Wei
    Piao, Song-zhe
    Mao, Xin-li
    Zhou, Xian-bin
    Wang, Yi
    Wu, Wei-dan
    Ye, Li-ping
    Li, Shao-wei
    FRONTIERS IN GENETICS, 2021, 12
  • [33] CIRCADIAN DYSREGULATION OF HUMAN DNA REPAIR GENES AND ELEVATED DNA DAMAGE IN SIMULATED NIGHT SHIFT SCHEDULE
    Van Dongen, Hans
    Koritala, Bala
    Porter, Kenneth
    Arshad, Osama
    Gajula, Rajendra
    Mitchell, Hugh
    Arman, Tarana
    Manjanatha, Mugimane
    Teeguarden, Justin
    McDermott, Jason
    Gaddameedhi, Shobhan
    SLEEP, 2022, 45 : A11 - A12
  • [34] The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer
    Gao, Dan
    Herman, James G.
    Guo, Mingzhou
    ONCOTARGET, 2016, 7 (24) : 37331 - 37346
  • [35] DNA DAMAGE REPAIR GENES REGULATE BLADDER INFLAMMATION
    Dru, Christopher
    Haldar, Subhash
    Bhowmick, Neil
    JOURNAL OF UROLOGY, 2015, 193 (04): : E224 - E224
  • [36] Implications of DNA damage and DNA repair on human diseases
    Nelson, Bryant C.
    Dizdaroglu, Miral
    MUTAGENESIS, 2020, 35 (01) : 1 - 3
  • [37] Human DNA glycosylases involved in the repair of oxidatively damaged DNA
    Ide, H
    Kotera, M
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2004, 27 (04) : 480 - 485
  • [38] ROLE AND IDENTIFICATION OF THE GENES INVOLVED IN HUMAN HYPERTENSION
    SOUBRIER, F
    BONNARDEAUX, A
    JOURNAL OF HUMAN HYPERTENSION, 1994, 8 (08) : 579 - 585
  • [39] Mutation landscape of genes involved in DNA-damage repair pathway among Chinese patients with prostate cancer
    Qiu, J.
    Wang, D.
    Qu, H.
    Yao, B.
    Ma, B.
    Ye, L.
    Zhong, W.
    Wang, Q.
    Xie, W.
    ANNALS OF ONCOLOGY, 2020, 31 : S533 - S533
  • [40] Insertional mutagenesis in Chlamydomonas reinhardtii: An effective strategy for the identification of new genes involved in the DNA damage response
    Gahurova, Dominika
    Krajciova, Daniela
    Reichwalderova, Katarina
    Slaninova, Miroslava
    EUROPEAN JOURNAL OF PROTISTOLOGY, 2022, 82
12345