QSAR STUDY OF ORTHO-PHENYLPHENOL LEUKOTRIENE B4 RECEPTOR ANTAGONISTS

被引：2

作者：

WIKEL, JH

SOFIA, MJ

SAUSSY, DL

BEMIS, KG

机构：

[1] Lilly Research Laboratories, Eli Lilly and Company, Indianapolis

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(01)80850-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

QSAR models for a series of o-phenylphenol LTB4 receptor antagonist have been developed with regression analysis. These models related specific features, electronic, size and shape, of the substituent with biological activity. The models have predictive value and may be useful in assisting future synthetic direction within this series of compounds.

引用

页码：795 / 800

页数：6

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