SELECTIVE LOCALIZATION OF C-ATRIAL NATRIURETIC PEPTIDE RECEPTORS IN THE RAT-BRAIN

被引：11

作者：

ZORAD, S ^{[1
]}

TSUTSUMI, K ^{[1
]}

SAAVEDRA, JM ^{[1
]}

机构：

[1] NIMH,CLIN SCI LAB,PHARMACOL SECT,9000 ROCKVILLE PIKE,BLDG 10,RM 2D-45,BETHESDA,MD 20892

来源：

BRAIN RESEARCH | 1992年 / 570卷 / 1-2期

关键词：

ATRIOPEPTIN; CLEARANCE RECEPTOR; CHOROID PLEXUS; MENINGES; OLFACTORY BULB;

D O I：

10.1016/0006-8993(92)90575-T

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We studied the distribution of C atrial natriuretic peptide (C-ANP) receptors in the rat brain after incubation with I-125-rANP, and competition with the selective C-ANP receptor competitor C-ANP(4-23) (10(-6) M). C-ANP receptors were selectively localized to a few structures, the external plexiform layer of the olfactory bulb, the arachnoid mater and the choroid plexus, and their amount corresponds to 25%, 75% and 35%, respectively, of the ANP specific binding. These data suggest specialized functions for C-ANP receptors in brain.

引用

页码：149 / 153

页数：5

共 50 条

[21] RECEPTORS FOR ATRIAL NATRIURETIC PEPTIDE ON ISOLATED RAT ADIPOCYTES
GOKE, R
GOKE, B
NOLL, B
RICHTER, G
FEHMANN, HC
ARNOLD, R
BIOMEDICAL RESEARCH-TOKYO, 1989, 10 (06): : 463 - 467
[22] REGULATION OF RECEPTORS FOR ATRIAL NATRIURETIC PEPTIDE IN THE RAT AND HUMAN
SCHIFFRIN, EL
CARDIOVASCULAR DRUGS AND THERAPY, 1988, 2 (04) : 493 - 500
[23] SELECTIVE DOWN-REGULATION OF RAT RENAL CLEARANCE RECEPTORS FOR ATRIAL-NATRIURETIC-PEPTIDE BY CHRONIC HIGH-SALT INTAKE - STUDY ON ISOLATED MEMBRANES USING I-125 LABELED C-ATRIAL NATRIURETIC PEPTIDE-(4-23)
MICHEL, H
BACKER, A
KRAMER, HJ
CLINICAL SCIENCE, 1992, 83 (02) : 139 - 142
[24] ATRIAL-NATRIURETIC-PEPTIDE INHIBITS AMILORIDE-SENSITIVE SODIUM UPTAKE IN RAT-BRAIN
KANDA, F
SARNACKI, P
ARIEFF, AI
AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 263 (02): : R279 - R283
[25] AUTORADIOGRAPHIC LOCALIZATION OF SOMATOSTATIN RECEPTORS IN RAT-BRAIN
TRAN, VT
UHL, GR
PERRY, DC
MANNING, DC
VALE, WW
PERRIN, MH
RIVIER, JE
MARTIN, JB
SNYDER, SH
EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 101 (3-4) : 307 - 309
[26] Estrogen receptors activate atrial natriuretic peptide in the rat heart
Jankowski, M
Rachelska, G
Wang, DH
McCann, SM
Gutkowska, J
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (20) : 11765 - 11770
[27] AUTORADIOGRAPHIC LOCALIZATION OF ATRIAL NATRIURETIC FACTOR RECEPTORS IN THE RAT TESTIS
PELLETIER, G
JOURNAL OF ANDROLOGY, 1988, 9 (05): : 352 - 355
[28] CHARACTERIZATION OF ATRIAL NATRIURETIC PEPTIDE RECEPTORS IN RAT CARDIAC SARCOLEMMA
RUGG, EL
CRAMB, G
AITON, JF
BIOCHEMICAL SOCIETY TRANSACTIONS, 1988, 16 (06) : 1022 - 1023
[29] AUTORADIOGRAPHIC LOCALIZATION OF RAT-I-125 ATRIAL-NATRIURETIC-PEPTIDE BINDING-SITES IN RAT-BRAIN, ADRENAL-GLAND, AND KIDNEY
OZAKI, M
NIWA, M
HIMENO, A
OHTA, H
IKARI, N
SHIMOMURA, T
NEUROCHEMICAL RESEARCH, 1986, 11 (12) : 1787 - 1787
[30] LOCALIZATION OF CALCITONIN GENE-RELATED PEPTIDE RECEPTORS IN THE RAT-BRAIN BY INVITRO AUTORADIOGRAPHY
SEXTON, PM
MASON, RT
MCKENZIE, JS
MOSELEY, JM
MARTIN, TJ
MENDELSOHN, FAO
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1986, 16 (01): : 167 - 167

← 1 2 3 4 5 →