NEW POLYENIC ANTIBIOTICS ACTIVE AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

被引：24

作者：

WATANABE, T ^{[1
]}

SUGIYAMA, T ^{[1
]}

TAKAHASHI, M ^{[1
]}

SHIMA, J ^{[1
]}

YAMASHITA, K ^{[1
]}

IZAKI, K ^{[1
]}

FURIHATA, K ^{[1
]}

SETO, H ^{[1
]}

机构：

[1] UNIV TOKYO,INST APPL MICROBIOL,BUNKYO KU,TOKYO 113,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 04期

关键词：

D O I：

10.7164/antibiotics.45.470

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The chemical structure of a unique polyenic antibiotic enacyloxin IIa (former name: fr. 2) produced by Frateuria (formerly Gluconobacter) sp. W-315 has been determined by extensive spectroscopic studies, in particular by NMR spectral analysis. It has a novel non-lactonic structure involving 3,4-dihydroxycyclohexanecarboxylic acid with a chlorine-containing polyenic and poly-hydroxy acyl side chain attached as an ester to the 3-hydroxyl substituent of the acid.

引用

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页码：470 / 475

页数：6

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