A double-hit High-grade B-cell lymphoma with three-way translocation t(3;8;14)(q27;q24;q32) involving BCL6, MYC, and IGH

被引：2
|
作者：
De Paoli, Elena [1 ]
Bandiera, Laura [1 ]
Ravano, Emanuele [2 ]
Cesana, Clara [1 ]
Grillo, Giovanni [2 ]
Mancini, Valentina [2 ]
De Canal, Gabriella [1 ]
Bonoldi, Emanuela [1 ]
Soriani, Silvia [1 ]
机构：
[1] ASST Grande Osped Metropolitano Niguarda, Dept Lab Med, Milan, Italy
[2] ASST Grande Osped Metropolitano Niguarda, Div Hematol, Milan, Italy
来源：
CLINICAL CASE REPORTS | 2018年 / 6卷 / 12期
关键词：
BCL6; double-hit lymphoma; High-grade B-cell lymphomas; MYC; t(3; 8; 14); three-way translocation;
D O I：
10.1002/ccr3.1871
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We describe an High-grade B-cell lymphoma case, in which a complex translocation t(3;8;14) with effects on the genes BCL6, MYC, and IGH, was detected. This case could be the first double-hit lymphoma with a single chromosome rearrangement causing the double effect with three genes involved.
引用
收藏
页码：2411 / 2415
页数：5
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