A double-hit High-grade B-cell lymphoma with three-way translocation t(3;8;14)(q27;q24;q32) involving BCL6, MYC, and IGH

被引：2

作者：

De Paoli, Elena ^{[1
]}

Bandiera, Laura ^{[1
]}

Ravano, Emanuele ^{[2
]}

Cesana, Clara ^{[1
]}

Grillo, Giovanni ^{[2
]}

Mancini, Valentina ^{[2
]}

De Canal, Gabriella ^{[1
]}

Bonoldi, Emanuela ^{[1
]}

Soriani, Silvia ^{[1
]}

机构：

[1] ASST Grande Osped Metropolitano Niguarda, Dept Lab Med, Milan, Italy

[2] ASST Grande Osped Metropolitano Niguarda, Div Hematol, Milan, Italy

来源：

CLINICAL CASE REPORTS | 2018年 / 6卷 / 12期

关键词：

BCL6; double-hit lymphoma; High-grade B-cell lymphomas; MYC; t(3; 8; 14); three-way translocation;

D O I：

10.1002/ccr3.1871

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe an High-grade B-cell lymphoma case, in which a complex translocation t(3;8;14) with effects on the genes BCL6, MYC, and IGH, was detected. This case could be the first double-hit lymphoma with a single chromosome rearrangement causing the double effect with three genes involved.

引用

页码：2411 / 2415

页数：5

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