5-(THIEN-2-YL)-2'-DEOXYURIDINE - A NEW AND POTENT INHIBITOR OF HERPES-SIMPLEX VIRUS TYPE-1 REPLICATION

被引：1
|
作者：
WIGERINCK, P
VANAERSCHOT, A
DECLERCQ, E
HERDEWIJN, P
机构：
[1] Rega Institute for Medical Research, Katholieke Universiteit Leuven
来源：
NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期
关键词：
D O I：
10.1080/07328319108046537
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
5-(Thien-2-yl)-2'-deoxyuridine, synthesized by coupling of 5-iodo-2'-deoxyuridine with 2-trimethylstannylthiophene in the presence of a Pd catalyst, shows potent anti-HSV-1 activity in vitro.
引用
收藏
页码：585 / 586
页数：2
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