4-METHYLTRITYL (MTT) - A NEW PROTECTING GROUP FOR THE SIDE-CHAIN PROTECTION OF ASN AND GLN IN SOLID-PHASE PEPTIDE-SYNTHESIS

被引:0
|
作者
SAX, B
DICK, F
TANNER, R
GOSTELI, J
机构
来源
PEPTIDE RESEARCH | 1992年 / 5卷 / 04期
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暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The trityl group was recently introduced for the protection of the side chain carboxamide function of asparagine and glutamine. The 4-methyltrityl (Mtt) group, a structural modification of trityl, is presented here and allows more rapid cleavage from the protected peptides. Procedures for the introduction of the group and comparative cleavage reactions are also presented.
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页码:245 / 246
页数:2
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