STUDIES ON SYNTHESIS, CHARACTERIZATION AND ANTITUMOR-ACTIVITY OF TERNARY COMPLEXES OF PYRUVIC-ACID ISONICOTINOYL HYDRAZONE AND 5-FLUOROURACIL-1-ACETIC ACID WITH RARE-EARTHS

被引：0

作者：

YANG, ZY ^{[1
]}

YANG, RD ^{[1
]}

WANG, LF ^{[1
]}

YANG, XP ^{[1
]}

机构：

[1] LANZHOU UNIV,DEPT CHEM,LANZHOU 730000,PEOPLES R CHINA

来源：

BULLETIN DES SOCIETES CHIMIQUES BELGES | 1995年 / 104卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thirteen ternary complexes of pyruvic acid isonicotinoyl hydrazone(H2PPFH) and 5-fluorouracil-1-acetic (HFAA) with rare earths have been synthesized in the paper. The structure and properties of the ternary complexes were determined by elemental analyses, infrared and ultraviolet spectra, molar conductivity and H-1 NMR. A general formula of the complexes is RE(PPFH)(FAA)2H2O (RE(III) = La-Yb). Antitumor activity of La(PPFH) (FAA).2H2O was tested with Leukaemia cells L1210and transplanted mouse tumor colon cancer C27. The results show that the inhibitory rate for C27 is 41.2%.

引用

页码：129 / 135

页数：7

共 50 条

[41] Three Ternary Rare Earth(III) Complexes Based on 3-[(4,6-Dimethyl-2-pyrimidinyl)thio]-propanoic Acid and 1,10-Phenanthroline: Synthesis, Crystal Structure and Antioxidant Activity
Chen, Xiao
Qu, Jian-Qiang
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2015, 641 (07): : 1301 - 1306
[42] Synthesis and Characterization of Zn(II) Complexes of 2-(7-Bromo-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl)acetohydrazide and Its Condensation Products with Pyruvic Acid and Isatin
Pulya, A. V.
Seifullina, I. I.
Skorokhod, L. S.
Vlasenko, V. G.
Trigub, A. L.
Rakipov, I. M.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (02) : 271 - 276
[43] Synthesis, characterization, spectroscopic and photophysical studies of ternary complexes of Eu(III) with 3-aminopyrazine-2-carboxylic acid (HL) and heterobiaryl ligands (2,2′-bipyridine and 1,10-phenanthroline)
De Sa, G.F., 1600, (196): : 1 - 2
[44] SYNTHESIS, CHARACTERIZATION, SPECTROSCOPIC AND PHOTOPHYSICAL STUDIES OF TERNARY COMPLEXES OF EU(III) WITH 3-AMINOPYRAZINE-2-CARBOXYLIC ACID (HL) AND HETEROBIARYL LIGANDS (2,2'-BIPYRIDINE AND 1,10-PHENANTHROLINE)
DESA, GF
NUNES, LHA
WANG, ZM
CHOPPIN, GR
JOURNAL OF ALLOYS AND COMPOUNDS, 1993, 196 (1-2) : 17 - 23
[45] Synthesis, characterization, anti-microbial and anti-fungal activity studies of four novel 2-aminopyridine and 2,4-dichloro-5-sulfamoylbenzoic acid salts and their Cu(II) complexes
Ilkimen, Halil
Gulbandilar, Aysel
KUWAIT JOURNAL OF SCIENCE, 2023, 50 (03)
[46] SYNTHESIS, CHARACTERIZATION AND BIOACTIVE EVALUATION OF COBALT(ΙΙ) AND COPPER(ΙΙ) COMPLEXES OF {4-[5-(5-SULFANYLIDENE-2,5DIHYDRO-1H-1,2,4-TRIAZOL-3-YL) FURAN-2-YL] PHENYL} ACETIC ACID
Khamees, Nidhal Meteab
Ahmed, Yusra Jalil
Al-Bayati, Sinan
Alazawi, Sarab
Rasheed, Anaam
BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2024, 38 (06) : 1595 - 1607
[47] Synthesis, structural characterization and biological studies of Ni(II), Cu(II) and Fe(III) complexes of hydrazone derived from 2-(2-(2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-ylidene)hydrazinyl)benzoic acid
Kumar, Shubha S.
Sadasivan, V.
Meena, Sher Singh
Sreepriya, R. S.
Biju, S.
INORGANICA CHIMICA ACTA, 2022, 536
[48] Synthesis, characterization and antioxidant activity of new dibasic tridentate ligands: X-ray crystal structures of DMSO adducts of 1,3-dimethyl-5-acetyl-barbituric acid o-hydroxybenzoyl hydrazone copper(II) complex
Giziroglu, Emrah
Aygun, Muhittin
Sarikurkcu, Cengiz
Kazar, Didem
Orhan, Nil
Firinci, Erkan
Soyleyici, H. Can
Gokcen, Ceren
INORGANIC CHEMISTRY COMMUNICATIONS, 2013, 36 : 199 - 205
[49] Synthesis, Characterization and in vitro Antimicrobial Activity of Co(II), Cu(II), Zn(II), Cd(II) and Sn(II) Ions with {[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]thio}acetic Acid
Win, Yip-Foo
Yousif, Emad
Majeed, Ahmed
Ha, Sie-Tiong
ASIAN JOURNAL OF CHEMISTRY, 2011, 23 (11) : 5009 - 5012
[50] Synthesis and structural characterization of nano-sized metal complexes of 3-(1-methyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-2-nitro-3-oxopropanoic acid. XRD, thermal, 3D modeling, and antitumor activity studies
El-ghamry, Mosad A.
El-Shafiy, H. F.
APPLIED ORGANOMETALLIC CHEMISTRY, 2021, 35 (06)

← 1 2 3 4 5 →