user

SYNTHESIS AND ANTIVIRAL EVALUATION OF 2 NEW CARBOCYCLIC PYRROLO[2,3-D]-PYRIMIDINE NUCLEOSIDES

被引：4
|
作者：
LEGRAVEREND, M
HUEL, C
ZERIAL, A
LEMAITRE, M
BISAGNI, E
机构：
[1] CTR UNIV ORSAY,INST CURIE,BIOL SECT,INSERM,U219,F-91405 ORSAY,FRANCE
[2] CTR RECH VITRY,RHONE POULENC SANTE,F-94403 VITRY,FRANCE
来源：
NUCLEOSIDES & NUCLEOTIDES | 1990年 / 9卷 / 05期
关键词：
D O I：
10.1080/07328319008045195
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
: Two new carbocyclic pyrrolo[2,3-d] pyrimidine nucleoside analogs related to the antiherpetic agent RP54 247 (8) have been synthesized. These compounds exhibited no antiviral activity in vitro toward herpes simplex virus type 1, human cytomegalovirus, and human immunodeficiency virus 1. © 1990, Taylor & Francis Group, LLC. All rights reserved.
引用
收藏
页码：639 / 647
页数：9
相关论文
共 50 条
  • [41] SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME ACYCLIC AND C-ACYCLIC PYRROLO[2,3-D]PYRIMIDINE NUCLEOSIDE ANALOGS
    BENNETT, SM
    NGUYENBA, N
    OGILVIE, KK
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (08) : 2162 - 2173
  • [42] SYNTHESIS, CYTO-TOXICITY, AND ANTIVIRAL ACTIVITY OF CERTAIN 7-[(2-HYDROXYETHOXY)METHYL]PYRROLO[2,3-D]PYRIMIDINE NUCLEOSIDES RELATED TO TOYOCAMYCIN AND SANGIVAMYCIN
    GUPTA, PK
    NASSIRI, MR
    COLEMAN, LA
    WOTRING, LL
    DRACH, JC
    TOWNSEND, LB
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (07) : 1420 - 1425
  • [43] TRICYCLIC NUCLEOSIDES .1. SYNTHESIS OF NEW TRICYCLIC RING-SYSTEM TETRAZOLO[1,5-C]PYRROLO[2,3-D]PYRIMIDINE AND CERTAIN TETRAZOLO[1,5-C]PYRROLO[2,3-D]PYRIMIDINE RIBONUCLEOSIDES
    SCHRAM, KH
    MANNING, SJ
    TOWNSEND, LB
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1975, 12 (05) : 1021 - 1023
  • [44] Design, Synthesis and Biological Evaluation of Histone Deacetylase Inhibitors Based on Pyrrolo[2,3-d]pyrimidine and Pyrrolo[2,3-b]pyridine Scaffolds
    Mao, Nian-Dong
    Gao, Yuan
    Dang, Xia-Wen
    Duan, Ji-Long
    Hui, Zi
    Che, Hao
    Xu, Yueying
    Zhang, Hang
    He, Xingrui
    Garrido, Carmen
    Ye, Xiang-Yang
    [J]. CHEMMEDCHEM, 2023, 18 (14)
  • [45] NOVEL PYRROLO[2,3-b]PYRIDINE AND PYRROLO[2,3-d] PYRIMIDINE DERIVATIVES: DESIGN, SYNTHESIS, AND STRUCTURE ELUCIDATION
    Hilmy, Khaled M. H.
    Kishk, Fawzya N. M.
    Shahen, Esmat B. A.
    Hawata, Mohamed A.
    [J]. BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2023, 37 (04) : 983 - 992
  • [46] REACTIONS WITH HETEROCYCLIC ENAMINONITRILES - SYNTHESIS OF PYRROLO[2,3-B]PYRIDINE, PYRROLO[2,3-D]PYRIMIDINE AND PYRROLE DERIVATIVES
    ABDELHAMID, AO
    ABDELGALIL, FM
    SALEH, SS
    [J]. HETEROCYCLES, 1988, 27 (08) : 1861 - 1866
  • [47] Synthesis of pyrrolo [2,3-d]pyrimidines
    Lloyd, AW
    [J]. DRUG DISCOVERY TODAY, 1996, 1 (02) : 83 - 84
  • [48] SYNTHESIS OF 7-GLYCOPYRANOSYL-5-OXO-PYRROLO[2,3-D]PYRIMIDINE AND 4-GLYCOPYRANOSYLAMINO-FURO[2,3-D]PYRIMIDINE DERIVATIVES
    NOGUERAS, M
    QUIJANO, ML
    SANCHEZ, A
    MELGAREJO, M
    [J]. NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2): : 373 - 374
  • [49] SYNTHESIS OF PYRROLO[2,3-D]PYRIMIDINES
    ROTH, HJ
    EGER, K
    [J]. ARCHIV DER PHARMAZIE, 1975, 308 (04) : 252 - 258
  • [50] REGIOSELECTIVE SYNTHESIS OF PYRROLO[2,3-D]-PYRIMIDINE-2,4-DIONES AND "PYRIDO[2,3-D]-PYRIMIDINE-2,4-DIONES
    TAMURA, Y
    SAKAGUCHI, T
    KAWASAKI, T
    KITA, Y
    [J]. HETEROCYCLES, 1975, 3 (02) : 183 - 186
12345