The role of melatonin in type 2 diabetes mellitus

被引:0
|
作者
Mikolajczyk, Melania [1 ]
机构
[1] Uniwersytet Med Lodzi, Klin Chorob Wewnetrznych, Oddzialem Diabetol & Farmakol Klin, Lodz, Poland
来源
CLINICAL DIABETOLOGY | 2013年 / 2卷 / 04期
关键词
type 2 diabetes mellitus; circadian rhythm; melatonin; melatonin receptors;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A negative relationship between shift work and an increased risk of some chronic diseases has been reported. Available data has shown that biological circadian rhythm disruption plays an important role in developing impaired glucose tolerance and type 2 diabetes (T2DM). This review article concerns the impact of the biological clock, melatonin, clock gene mutations and single nucleotide polymorphisms melatonin receptor gene on glucose homeostasis in experimental and clinical studies.
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页码:136 / 143
页数:8
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