BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA

被引：61
|
作者：
SANGWAN, RS [1 ]
AGARWAL, K [1 ]
LUTHRA, R [1 ]
THAKUR, RS [1 ]
SINGHSANGWAN, N [1 ]
机构：
[1] CENT INST MED & AROMAT PLANTS, POST BAG 1, PO RSM, LUCKNOW, INDIA
来源：
PHYTOCHEMISTRY | 1993年 / 34卷 / 05期
关键词：
ARTEMISIA-ANNUA; COMPOSITAE; ARTEMISININ BIOSYNTHESIS; IN-VIVO; IN-VITRO CONVERSION;
D O I：
10.1016/0031-9422(91)80019-W
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In Artemisia annua, [C-14]arteannuic acid was incorporated into arteannuin-B as well as artemisinin, both in vivo and in a cell free system. Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations under in vitro conditions. The results suggest that arteannuic acid might be a common precursor for arteannuin-B and artemisinin synthesis.
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页码：1301 / 1302
页数：2
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