BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA

被引：61

作者：

SANGWAN, RS ^{[1
]}

AGARWAL, K ^{[1
]}

LUTHRA, R ^{[1
]}

THAKUR, RS ^{[1
]}

SINGHSANGWAN, N ^{[1
]}

机构：

[1] CENT INST MED & AROMAT PLANTS, POST BAG 1, PO RSM, LUCKNOW, INDIA

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 05期

关键词：

ARTEMISIA-ANNUA; COMPOSITAE; ARTEMISININ BIOSYNTHESIS; IN-VIVO; IN-VITRO CONVERSION;

D O I：

10.1016/0031-9422(91)80019-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In Artemisia annua, [C-14]arteannuic acid was incorporated into arteannuin-B as well as artemisinin, both in vivo and in a cell free system. Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations under in vitro conditions. The results suggest that arteannuic acid might be a common precursor for arteannuin-B and artemisinin synthesis.

引用

页码：1301 / 1302

页数：2

共 50 条

[31] A LARGE-SCALE EXTRACTION TECHNIQUE OF ARTEMISININ FROM ARTEMISIA-ANNUA
ELSOHLY, HN
CROOM, EM
ELFERALY, FS
ELSHEREI, MM
JOURNAL OF NATURAL PRODUCTS, 1990, 53 (06): : 1560 - 1564
[32] SELECTION AND MICROPROPAGATION OF HIGH ARTEMISININ PRODUCING CLONES OF ARTEMISIA-ANNUA L
ELHAG, HM
ELDOMIATY, MM
ELFERALY, FS
MOSSA, JS
ELOLEMY, MM
PHYTOTHERAPY RESEARCH, 1992, 6 (01) : 20 - 24
[33] STEREOSELECTIVE TOTAL SYNTHESIS OF (+)-ARTEMISININ, THE ANTIMALARIAL CONSTITUENT OF ARTEMISIA-ANNUA L
AVERY, MA
CHONG, WKM
JENNINGSWHITE, C
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (03) : 974 - 979
[34] Studies on the biosynthesis of arteannuin Ⅲ.Arteannuic acid as a key intermediate in the biosyntheses of arteannuin and arteannuin B
WANG Yu XIA Zhi-Qiang ZHOU Feng-Yi WU Yu-Lin HUANG Jing-Jian WANG Zhi-Zhong Shanghai Institute of Organic Chemistry
Academia Sinica
Shanghai
Acta Chimica Sinica(English Edition), 1988, (04) : 386 - 387
[35] CRYSTAL-STRUCTURE OF ARTEMISINIC ACID - A POSSIBLE BIOGENETIC PRECURSOR OF ANTIMALARIAL ARTEMISININ FROM ARTEMISIA-ANNUA
MISRA, LN
AHMAD, A
THAKUR, RS
LOTTER, H
WAGNER, H
JOURNAL OF NATURAL PRODUCTS, 1993, 56 (02): : 215 - 219
[36] PRODUCTION OF THE NEW ANTIMALARIAL DRUG ARTEMISININ IN SHOOT CULTURES OF ARTEMISIA-ANNUA L
WOERDENBAG, HJ
LUERS, JFJ
VANUDEN, W
PRAS, N
MALINGRE, TM
ALFERMANN, AW
PLANT CELL TISSUE AND ORGAN CULTURE, 1993, 32 (02) : 247 - 257
[37] STRESSOR EFFECTS ON ARTEMISININ (QUIGHOUSU) PRODUCTION IN SHOOT CULTURES OF ARTEMISIA-ANNUA L
CHEN, FT
KUDAKASSERIL, JG
MARTINEZ, B
LAM, L
STABA, EJ
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY, 1986, 22 (03): : A52 - A52
[38] ISOLATION OF ARTEMISININ [QINGHAOSU) FROM ARTEMISIA-ANNUA GROWING IN THE UNITED-STATES
KLAYMAN, DL
LIN, AJ
ACTON, N
SCOVILL, JP
HOCH, JM
MILHOUS, WK
THEOHARIDES, AD
JOURNAL OF NATURAL PRODUCTS, 1984, 47 (04): : 715 - 717
[39] ESTABLISHMENT OF NORMAL AND TRANSFORMED ROOT CULTURES OF ARTEMISIA-ANNUA L FOR ARTEMISININ PRODUCTION
JAZIRI, M
SHIMOMURA, K
YOSHIMATSU, K
FAUCONNIER, ML
MARLIER, M
HOMES, J
JOURNAL OF PLANT PHYSIOLOGY, 1995, 145 (1-2) : 175 - 177
[40] ARTEMISININ, RELATED SESQUITERPENES, AND ESSENTIAL OIL IN ARTEMISIA-ANNUA DURING A VEGETATION PERIOD IN VIETNAM
WOERDENBAG, HJ
PRAS, N
CHAN, NG
BANG, BT
BOS, R
VANUDEN, W
Y, PV
BOI, NV
BATTERMAN, S
LUGT, CB
PLANTA MEDICA, 1994, 60 (03) : 272 - 275

← 1 2 3 4 5 →