BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA

被引:61
|
作者
SANGWAN, RS [1 ]
AGARWAL, K [1 ]
LUTHRA, R [1 ]
THAKUR, RS [1 ]
SINGHSANGWAN, N [1 ]
机构
[1] CENT INST MED & AROMAT PLANTS, POST BAG 1, PO RSM, LUCKNOW, INDIA
关键词
ARTEMISIA-ANNUA; COMPOSITAE; ARTEMISININ BIOSYNTHESIS; IN-VIVO; IN-VITRO CONVERSION;
D O I
10.1016/0031-9422(91)80019-W
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In Artemisia annua, [C-14]arteannuic acid was incorporated into arteannuin-B as well as artemisinin, both in vivo and in a cell free system. Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations under in vitro conditions. The results suggest that arteannuic acid might be a common precursor for arteannuin-B and artemisinin synthesis.
引用
收藏
页码:1301 / 1302
页数:2
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