SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 4-O-ETHYLTHYMIDINE

被引：1
|
作者：
PEDROSO, E
FERNANDEZ, D
PALOM, Y
ERITJA, R
机构：
[1] Department of Organic Chemistry, University of Barcelona, E-08028 Barcelona
来源：
NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期
关键词：
D O I：
10.1080/07328319108046551
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Use of p-nitrophenylethyl base protecting groups together with phosphite-triester solid-phase methodology allows the rapid and efficient preparation of oligonucleotides bearing the mutagenic base 4-O-ethylthymine, while standard base protecting groups are not compatible with the presence of this base.
引用
收藏
页码：623 / 624
页数：2
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