Synthesis and binding properties of oligonucleotides containing an azobenzene linker

被引：17

作者：

Yamana, K ^{[1
]}

Yoshikawa, A ^{[1
]}

Noda, R ^{[1
]}

Nakano, H ^{[1
]}

机构：

[1] Himeji Inst Technol, Dept Appl Chem, Himeji, Hyogo 67122, Japan

来源：

NUCLEOSIDES & NUCLEOTIDES | 1998年 / 17卷 / 1-3期

关键词：

D O I：

10.1080/07328319808005172

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Incorporation of an azobenzene-4,4'-diamide group via a linker arm into the 3'-hydroxyl function of one oligonucleotide segment and the 5'-OH of other oligonucleotide has been described. The binding of the oligonucleotides containing the azobenzene linker was investigated by UV melting behaviors. The azobenzene linker has been shown to be useful as an effective bridge for stabilizing hairpin duplex and triplex.

引用

页码：233 / 242

页数：10

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