ASYMMETRIC-SYNTHESIS OF (-)-NEOPODOPHYLLOTOXIN

被引：53
|
作者：
CHARLTON, JL
KOH, K
机构：
[1] Department of Chemistry, University of Manitoba, Winnipeg, Manitoba
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 05期
关键词：
D O I：
10.1021/jo00031a033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A five-step asymmetric synthesis of neopodophyllotoxin in 18% overall yield and optical purity > 97%, starting from 6-(3,4,5-trimethoxybenzyl)piperonal (6) and the fumarate of (S)-methyl mandelate (8), is described.
引用
收藏
页码：1514 / 1516
页数：3
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