A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report

被引:0
|
作者
Merhaben, Salma [1 ]
Ayadi, Shema [1 ]
Tangour, Monia [2 ]
Boujelbene, Nadia [2 ]
Ghariani, Rayfa [3 ]
Mouelhi, Leila [1 ]
Merhaben, Fathi [4 ]
机构
[1] Charles Nicolle Hosp, Gastroenterol Dept, Tunis 1006, Tunisia
[2] Salah Azaiez Inst, Histopathol Dept, Tunis 1007, Tunisia
[3] El Amen Private Hosp, Radiol Dept, Nabeul 8000, Tunisia
[4] El Amen Private Hosp, Gastroenterol Dept, Nabeul 8000, Tunisia
来源
关键词
anti-TNF therapy; Crohn's disease; diffuse large -B cell lymphoma; primary hepatic lymphoma; thiopurine;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Primary hepatic lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed as a risk factor for primary hepatic lymphoma. We report an intriguing case study, featuring a 23-year-old male patient with Crohn's Disease who had been receiving a combination therapy of thiopurine and anti-TNF for 6 years and was diagnosed with primary hepatic diffuse large B-cell lymphoma.
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页数:7
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