A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report

被引：0

作者：

Merhaben, Salma ^{[1
]}

Ayadi, Shema ^{[1
]}

Tangour, Monia ^{[2
]}

Boujelbene, Nadia ^{[2
]}

Ghariani, Rayfa ^{[3
]}

Mouelhi, Leila ^{[1
]}

Merhaben, Fathi ^{[4
]}

机构：

[1] Charles Nicolle Hosp, Gastroenterol Dept, Tunis 1006, Tunisia

[2] Salah Azaiez Inst, Histopathol Dept, Tunis 1007, Tunisia

[3] El Amen Private Hosp, Radiol Dept, Nabeul 8000, Tunisia

[4] El Amen Private Hosp, Gastroenterol Dept, Nabeul 8000, Tunisia

来源：

FUTURE SCIENCE OA | 2023年

关键词：

anti-TNF therapy; Crohn's disease; diffuse large -B cell lymphoma; primary hepatic lymphoma; thiopurine;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Primary hepatic lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed as a risk factor for primary hepatic lymphoma. We report an intriguing case study, featuring a 23-year-old male patient with Crohn's Disease who had been receiving a combination therapy of thiopurine and anti-TNF for 6 years and was diagnosed with primary hepatic diffuse large B-cell lymphoma.

引用

页数：7

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