IMMUNOGLOBULIN G-SPECIFIC AND IMMUNOGLOBULIN M-SPECIFIC ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF DENGUE ANTIBODIES

被引:0
|
作者
DITTMAR, D [1 ]
CLEARY, TJ [1 ]
CASTRO, A [1 ]
机构
[1] UNIV MIAMI, SCH MED, DEPT PATHOL, HORMONE RES LAB, MIAMI, FL 33101 USA
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中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
An enzyme-linked immunosorbent assay [ELISA] for the detection of antibodies [Ab] to dengue virus is described. This method correlates well with a hemagglutination inhibition technique. The ELISA can be specific for human immunoglobulin (Ig) M Ab when a .mu.-chain-specific antiglobulin-enzyme conjugate and fractionated serum are employed. By using this technique, dengue IgM Ab were demonstrated in a [human] infant suspected of having a recent dengue infection.
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页码:498 / 502
页数:5
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