HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF OLIGOSACCHARIDE ALDITOLS AND GLYCOPEPTIDES ON A GRAPHITIZED CARBON COLUMN

被引：72
|
作者：
DAVIES, M [1 ]
SMITH, KD [1 ]
HARBIN, AM [1 ]
HOUNSELL, EF [1 ]
机构：
[1] CLIN RES CTR, GLYCOCONJUGATES SECT, WATFORD RD, HARROW HA1 3UJ, MIDDX, ENGLAND
来源：
JOURNAL OF CHROMATOGRAPHY | 1992年 / 609卷 / 1-2期
关键词：
D O I：
10.1016/0021-9673(92)80155-N
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The chromatographic behaviour of oligosaccharide alditols and glycopeptides containing neutral and acetamido sugars and sialic acid has been investigated on a HyperCarb porous graphitised carbon column. The alditols were substantially retained and could be eluted in 0-25% acetonitrile-0.05% trifluoroacetic acid in 0.05% aqueous trifluoroacetic acid between 3-30 min for mono- to hexasaccharides. Elution patterns were based on both size, charge and linkage such that isomeric compounds could be separated from each other.
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页码：125 / 131
页数：7
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