A NEW FAMILY OF 5-CARBON IMINOALDITOLS WHICH ARE POTENT GLYCOSIDASE INHIBITORS

被引：79
|
作者：
BERNOTAS, RC [1 ]
PAPANDREOU, G [1 ]
URBACH, J [1 ]
GANEM, B [1 ]
机构：
[1] CORNELL UNIV,DEPT CHEM,BAKER LAB,ITHACA,NY 14853
来源：
TETRAHEDRON LETTERS | 1990年 / 31卷 / 24期
关键词：
D O I：
10.1016/S0040-4039(00)97405-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of 1,5-dideoxy-1,5-imino-D-xylitol 2 (and the enantiomeric iminoalditols 3 and 4) is described. Alditol 2 compares favorably with 1-deoxynojirimycin 1 as a potent inhibitor of β-glucosidase. © 1990.
引用
收藏
页码：3393 / 3396
页数：4
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