COMPARISON OF THERAPEUTIC ROUTES IN EXPERIMENTAL PSEUDOMONAS KERATITIS

被引：33
|
作者：
DAVIS, SD
SARFF, LD
HYNDIUK, RA
机构：
[1] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT PEDIAT, MILWAUKEE, WI 53233 USA
[2] MILWAUKEE CTY MED COMPLEX, CORNEA EXTERNAL EYE DIS UNIT, MILWAUKEE, WI USA
[3] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT OPHTHALMOL, MILWAUKEE, WI 53233 USA
[4] MILWAUKEE CTY MED COMPLEX, INST EYE, MILWAUKEE, WI USA
来源：
AMERICAN JOURNAL OF OPHTHALMOLOGY | 1979年 / 87卷 / 05期
关键词：
D O I：
10.1016/0002-9394(79)90309-X
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The efficacy of tobramycin administered by topical, i.m. and subconjunctival routes in guinea pigs and rabbits with experimental Pseudomonas keratitis was determined. The topical route of administration was consistently more effective than either subconjunctival or i.m. routes. Subconjunctival injection of antibiotic did not enhance the effectiveness of topical therapy in either guinea pigs or rabbits. Tobramycin i.m. was more effective than saline in guinea pigs with keratitis but not in rabbits with keratitis.
引用
收藏
页码：710 / 716
页数：7
相关论文
共 50 条
  • [31] Amniotic Membrane Transplantation for the Treatment of Pseudomonas Keratitis in Experimental Rabbits
    Nejabat, M.
    Masoumpour, M. B.
    Eghtedari, M.
    Azarpira, N.
    Ashraf, M. J.
    Astane, A. R.
    IRANIAN RED CRESCENT MEDICAL JOURNAL, 2009, 11 (02) : 149 - 154
  • [32] EXPERIMENTAL PSEUDOMONAS KERATITIS IN THE RABBIT - BACTERIOLOGIC, CLINICAL, AND MICROSCOPIC OBSERVATIONS
    VANHORN, DL
    DAVIS, SD
    HYNDIUK, RA
    PEDERSON, HJ
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1981, 20 (02) : 213 - 221
  • [33] Pseudomonas aeruginosa LasA protease in treatment of experimental staphylococcal keratitis
    Barequet, IS
    Ben Simon, GJ
    Safrin, M
    Ohman, DE
    Kessler, E
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (05) : 1681 - 1687
  • [34] EXPERIMENTAL PSEUDOMONAS KERATITIS - TREATMENT WITH AND EVALUATION OF CARBENICILLIN AND GENTAMICIN IN COMBINATION
    BOHIGIAN, G
    OKUMOTO, M
    VALENTON, M
    ARCHIVES OF OPHTHALMOLOGY, 1971, 86 (04) : 432 - &
  • [35] ANTIBIOTIC THERAPY OF EXPERIMENTAL PSEUDOMONAS KERATITIS IN GUINEA-PIGS
    DAVIS, SD
    SARFF, LD
    HYNDIUK, RA
    ARCHIVES OF OPHTHALMOLOGY, 1977, 95 (09) : 1638 - 1643
  • [36] Effect of vitamin A deficiency on the early response to experimental Pseudomonas keratitis
    Twining, SS
    Zhou, XY
    Schulte, DP
    Wilson, PM
    Fish, B
    Moulder, J
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (04) : 511 - 522
  • [37] RELATIONSHIP BETWEEN PROTEASES AND DESCEMETOCELE FORMATION IN EXPERIMENTAL PSEUDOMONAS KERATITIS
    TWINING, SS
    DAVIS, SD
    HYNDIUK, RA
    CURRENT EYE RESEARCH, 1986, 5 (07) : 503 - 510
  • [38] EXPERIMENTAL PSEUDOMONAS-AERUGINOSA ULCERATIVE KERATITIS MODEL IN THE DOG
    WYMAN, M
    SWANSON, C
    KOWALSKI, JJ
    POWERS, JD
    BORASKI, EA
    AMERICAN JOURNAL OF VETERINARY RESEARCH, 1983, 44 (06) : 1135 - 1140
  • [39] The effectiveness of two ciprofloxacin formulations for experimental Pseudomonas and Staphylococcus keratitis
    Engel, LS
    Callegan, MC
    Hill, JM
    Folkens, AT
    Shimomura, Y
    OCallaghan, RJ
    JAPANESE JOURNAL OF OPHTHALMOLOGY, 1996, 40 (02) : 212 - 219
  • [40] Clinico-microbiological Features and Treatment Outcomes of Serratia Keratitis and Comparison with Pseudomonas aeruginosa Keratitis
    Kate, Anahita
    Bagga, Bhupesh
    Ponnapati, Lakshmi Prasanna
    Singh, Shalini
    Shah, Sahil
    Mohamed, Ashik
    Joseph, Joveeta
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2023, 31 (03) : 515 - 519
12345