COMPARISON OF THERAPEUTIC ROUTES IN EXPERIMENTAL PSEUDOMONAS KERATITIS

被引：33
|
作者：
DAVIS, SD
SARFF, LD
HYNDIUK, RA
机构：
[1] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT PEDIAT, MILWAUKEE, WI 53233 USA
[2] MILWAUKEE CTY MED COMPLEX, CORNEA EXTERNAL EYE DIS UNIT, MILWAUKEE, WI USA
[3] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT OPHTHALMOL, MILWAUKEE, WI 53233 USA
[4] MILWAUKEE CTY MED COMPLEX, INST EYE, MILWAUKEE, WI USA
来源：
AMERICAN JOURNAL OF OPHTHALMOLOGY | 1979年 / 87卷 / 05期
关键词：
D O I：
10.1016/0002-9394(79)90309-X
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The efficacy of tobramycin administered by topical, i.m. and subconjunctival routes in guinea pigs and rabbits with experimental Pseudomonas keratitis was determined. The topical route of administration was consistently more effective than either subconjunctival or i.m. routes. Subconjunctival injection of antibiotic did not enhance the effectiveness of topical therapy in either guinea pigs or rabbits. Tobramycin i.m. was more effective than saline in guinea pigs with keratitis but not in rabbits with keratitis.
引用
收藏
页码：710 / 716
页数：7
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