AGE, ENVIRONMENTAL-FACTORS AND DRUG-METABOLISM

被引：29
|
作者：
OMAHONY, MS [1 ]
WOODHOUSE, KW [1 ]
机构：
[1] UNIV WALES COLL CARDIFF,CARDIFF ROYAL INFIRM,DEPT GERIATR MED,CARDIFF,S GLAM,WALES
来源：
PHARMACOLOGY & THERAPEUTICS | 1994年 / 61卷 / 1-2期
关键词：
AGING; DRUG METABOLISM;
D O I：
10.1016/0163-7258(94)90066-3
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Both ageing and the environment have a significant impact on xenobiotic metabolism. Furthermore, there is some evidence from in vivo studies that the elderly respond to environmental changes to a lesser degree than younger individuals. This article reviews the available evidence and concentrates on possible underlying mechanisms.
引用
收藏
页码：279 / 287
页数：9
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