AGE, ENVIRONMENTAL-FACTORS AND DRUG-METABOLISM

被引：29

作者：

OMAHONY, MS ^{[1
]}

WOODHOUSE, KW ^{[1
]}

机构：

[1] UNIV WALES COLL CARDIFF,CARDIFF ROYAL INFIRM,DEPT GERIATR MED,CARDIFF,S GLAM,WALES

来源：

PHARMACOLOGY & THERAPEUTICS | 1994年 / 61卷 / 1-2期

关键词：

AGING; DRUG METABOLISM;

D O I：

10.1016/0163-7258(94)90066-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Both ageing and the environment have a significant impact on xenobiotic metabolism. Furthermore, there is some evidence from in vivo studies that the elderly respond to environmental changes to a lesser degree than younger individuals. This article reviews the available evidence and concentrates on possible underlying mechanisms.

引用

页码：279 / 287

页数：9

共 50 条

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