A SIMPLE ENANTIOSELECTIVE SYNTHESIS OF (-)-S-CAMPHONANIC AND (+)-R-CAMPHONANIC ACIDS

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作者
ABAD, A
AGULLO, C
ARNO, M
CUNAT, AC
ZARAGOZA, RJ
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A four step enantioselective synthesis of 1S- and IR-1,2,2-trimethylcyclopentanecarboxylic acids [(S)- and (R)-camphonanic acid, (-)-1 and (+)-1 respectively] has been achieved from beta-cyclogeraniol, using a Katsuki-Sharpless asymmetric epoxidation and a pinacollic rearrangement as key synthetic steps.
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页码:895 / 896
页数:2
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