The level of transglutaminase (TGase) expressed in various tumor cell lines was investigated. We found that each cell line could be categorized into three distinct groups, that is, (i) cell lines with low or negligible TGase activity, (ii) cell lines with significant or high TGase activity and immunoreactive to a monoclonal antibody against tissue type TGase, and (iii) cell lines with significant or high TGase activity but not immunoreactive to the antibody. Results reported here argue against the former proposal that tissue-type TGase is expressed at a lower level in malignant cells compared to the level in normal cells.
机构:
Helmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, GermanyHelmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, Germany
Raschke, Felix
Barrick, Thomas R.
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St Georges Univ London, Neurosci Res Ctr, Mol & Clin Sci Res Inst, Cranmer Terrace, London SW17 0RE, EnglandHelmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, Germany
Barrick, Thomas R.
Jones, Timothy L.
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St Georges Univ Hosp NHS Fdn Trust, Atkinson Morley Dept Neurosurg, Blackshaw Rd, London SW17 0QT, EnglandHelmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, Germany
机构:
Univ Lincoln, Lab Vis Engn, Sch Comp Sci, Lincoln LN6 7TS, EnglandHelmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, Germany
Ye, Xujiong
Howe, Franklyn A.
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St Georges Univ London, Neurosci Res Ctr, Mol & Clin Sci Res Inst, Cranmer Terrace, London SW17 0RE, EnglandHelmholtz Zentrum Dresden Rossendorf, Inst Radiooncol OncoRay, Rossendorf, Germany
机构:
Thomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
Mashayekhi, Arman
Tuncer, Samuray
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机构:
Istanbul Univ, Dept Ophthalmol, Istanbul, TurkeyThomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
Tuncer, Samuray
Shields, Carol L.
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机构:
Thomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
Shields, Carol L.
Shields, Jerry A.
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机构:
Thomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
机构:
Osaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, JapanOsaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan
Shimatani, Akiyoshi
Hoshi, Manabu
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机构:
Osaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, JapanOsaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan
Hoshi, Manabu
Oebisu, Naoto
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Osaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, JapanOsaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan
Oebisu, Naoto
Takada, Naoki
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机构:
Osaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, JapanOsaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan
Takada, Naoki
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机构:
Ban, Yoshitaka
Nakamura, Hiroaki
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机构:
Osaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, JapanOsaka City Univ, Dept Orthoped Surg, Grad Sch Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan
机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Shim, BS
Kang, BH
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Kang, BH
Hong, YK
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Hong, YK
Kim, HK
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Kim, HK
Lee, IH
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Lee, IH
Lee, SY
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Lee, SY
Lee, YJ
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Lee, YJ
Lee, SK
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机构:Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea
Lee, SK
Joe, YA
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机构:
Catholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South KoreaCatholic Univ Korea, Inst Canc Res, Catholic Res Inst Med Sci, Seoul 137701, South Korea