COMPARISON OF RUFLOXACIN AND NORFLOXACIN EFFECTS ON FECAL FLORA

被引：5
|
作者：
MARCO, F
GIMENEZ, MJ
DEANTA, MTJ
MARCOS, MA
SALVA, P
AGUILAR, L
机构：
[1] SMITHKLINE BEECHAM SA, DEPT MED, E-28034 MADRID, SPAIN
[2] HOSP GERMANS TRIAS & PUJOL, DEPT CLIN PHARMACOL, E-08916 BADALONA, SPAIN
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1995年 / 35卷 / 06期
关键词：
D O I：
10.1093/jac/35.6.895
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The suppression of faecal Escherichia coli by quinolones was studied in a randomized cross-over phase I trial with single oral doses of 400 mg rufloxacin or norfloxacin. Both drugs caused >70% decontamination in a similar number of subjects in the 72 h post-dose period (83% vs 100% respectively), but suppression of E. coli at 168 h was significantly (P < 0.05) higher after rufloxacin (83.3 vs 40%).
引用
收藏
页码：895 / 901
页数：7
相关论文
共 50 条
  • [41] THE FECAL FLORA OF THE NORMAL COW
    WILSSENS, A
    BUTTIAUX, R
    ANNALES DE L INSTITUT PASTEUR, 1958, 94 (03): : 332 - 340
  • [42] EFFECT OF CEFOPERAZONE ON FECAL FLORA
    ALESTIG, K
    CARLBERG, H
    NORD, CE
    TROLLFORS, B
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1983, 12 (02) : 163 - 167
  • [43] NORMAL FECAL FLORA IN ADULTS
    SCHMIDT, F
    SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT, 1968, 98 (14) : 532 - &
  • [44] STABILITY OF HUMAN FECAL FLORA
    BORNSIDE, GH
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1978, 31 (10): : S141 - S144
  • [45] Effects of Human Fecal Flora on Intestinal Morphology and Mucosal Immunity in Human Flora-associated Piglet
    Che, C.
    Pang, X.
    Hua, X.
    Zhang, B.
    Shen, J.
    Zhu, J.
    Wei, H.
    Sun, L.
    Chen, P.
    Cui, L.
    Zhao, L.
    Yang, Q.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2009, 69 (03) : 223 - 233
  • [46] DEVELOPMENT OF THE INFANT FECAL FLORA
    BORRIELLO, SP
    JOURNAL OF MEDICAL MICROBIOLOGY, 1982, 15 (04) : R27 - R27
  • [47] NORMAL FECAL FLORA OF MAN
    GALL, LS
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1970, 23 (11): : 1457 - &
  • [48] INFLUENCE OF OFLOXACIN ON THE FECAL FLORA
    MIDTVEDT, T
    DRUGS, 1987, 34 : 154 - 158
  • [49] FECAL FLORA IN ULCERATIVE COLITIS
    THAYER, WR
    GASTROENTEROLOGY, 1968, 55 (02) : 292 - &
  • [50] ORAL AND FECAL FLORA OF MICE
    SLACK, GL
    BOWDEN, GWH
    JOURNAL OF DENTAL RESEARCH, 1963, 42 (05) : 1086 - &
12345