Synthesis of some new piperazine-N,N'-bis-substituted derivatives as potential biologically active agents

被引:0
|
作者
AbdelHamide, SG [1 ]
ElShaaer, HM [1 ]
Allimony, HA [1 ]
AbdelAziz, SA [1 ]
AbdelRahman, RM [1 ]
机构
[1] AIN SHAMS UNIV,FAC EDUC,DEPT CHEM,CAIRO,EGYPT
来源
CHEMICAL PAPERS-CHEMICKE ZVESTI | 1995年 / 49卷 / 03期
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In a search for new bactericidal and fungicidal agents some new piperazine-N,N'-bis-substituted derivatives have been prepared and characterized by their elemental analysis, IR, H-1 NMR, and mass spectral data. The antibacterial and antifungal activities of all prepared compounds have been determined using Gentamycin as standard antibiotic. Some compounds showed a high activity equivalent to that of the standard towards Escherichia coli, Serratia marcescens, Bacillus cereus, Staphylococcus aureus, and Candida albicans.
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页码:142 / 148
页数:7
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