TRANSFORMATION OF POLYCYTHEMIA-VERA TO PH-POSITIVE CHRONIC MYELOGENOUS LEUKEMIA

被引：25
|
作者：
HAQ, AU [1 ]
机构：
[1] VET ADM MED CTR,SHREVEPORT,LA
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 1990年 / 35卷 / 02期
关键词：
CML; Conversion; p; vera;
D O I：
10.1002/ajh.2830350209
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A patient with polycythemia vera (PV) developed chronic myelogenous leukemia (CML) 8 years after his initial presentation with erythrocytosis. The patient received a total of 3.5‐7 g of chlorambucil over an approximate period of 5 years. Transformation of PV to CML is very unusual; only three substantiated cases had been reported in literature until 1975, and none has been described since then. All patients received either 32P or chemotherapy for PV treatment, suggesting that irradiation and alkylating agents may have played a role in the transformation to CML. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码：110 / 113
页数：4
相关论文
共 50 条
  • [21] MALIGNANT HISTIOCYTOSIS OCCURRING WITH ACUTE MYELOGENOUS LEUKEMIA IN A PATIENT WITH LONGSTANDING POLYCYTHEMIA-VERA
    BAER, MR
    GLEATON, JH
    SALHANY, KE
    GLICK, AD
    CANCER, 1987, 59 (03) : 489 - 495
  • [22] DEVELOPMENT OF CHRONIC LYMPHOCYTIC-LEUKEMIA IN A PATIENT WITH POLYCYTHEMIA-VERA
    PAPAYANNIS, AG
    NIKIFORAKIS, E
    AANAGNOSTOUKERAMIDA, D
    SCANDINAVIAN JOURNAL OF HAEMATOLOGY, 1982, 29 (01): : 65 - 69
  • [23] FURTHER CYTOGENETIC EVIDENCE FOR A MULTISTEP PATHOGENESIS OF PH-POSITIVE CHRONIC MYELOGENOUS LEUKEMIA
    BARBIERI, D
    FERRARESI, P
    CASTOLDI, G
    CANCER GENETICS AND CYTOGENETICS, 1985, 14 (1-2) : 111 - 117
  • [24] REMISSION OF LEUKEMIA ASSOCIATED WITH POLYCYTHEMIA-VERA
    PERLIN, E
    GRANATIR, RG
    ROCHE, J
    MOQUIN, RB
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1973, 223 (02): : 192 - 192
  • [25] POLYCYTHEMIA-VERA TERMINATING IN CHRONIC NEUTROPHILIC LEUKEMIA - REPORT OF A CASE
    IURLO, A
    FOA, P
    MAIOLO, AT
    LUKSCH, R
    CAPSONI, F
    POLLI, EE
    AMERICAN JOURNAL OF HEMATOLOGY, 1990, 35 (02) : 139 - 139
  • [26] POLYCYTHEMIA-VERA AND ACUTE-LEUKEMIA
    NEU, LT
    SHUMAN, MA
    BROWN, EB
    ANNALS OF INTERNAL MEDICINE, 1975, 83 (05) : 672 - 673
  • [27] ACUTE-LEUKEMIA IN POLYCYTHEMIA-VERA
    LANDAW, SA
    SEMINARS IN HEMATOLOGY, 1976, 13 (01) : 33 - 48
  • [28] SERUM MYELOPEROXIDASE IN LEUKEMIA AND POLYCYTHEMIA-VERA
    MALMQUIST, J
    SCANDINAVIAN JOURNAL OF HAEMATOLOGY, 1972, 9 (04): : 311 - +
  • [29] ACUTE-LEUKEMIA IN POLYCYTHEMIA-VERA
    PEDERSENBJERGAARD, J
    PHILIP, P
    NEW ENGLAND JOURNAL OF MEDICINE, 1981, 305 (06): : 342 - 343
  • [30] TERMINAL LYMPHOBLASTIC TRANSFORMATION IN POLYCYTHEMIA-VERA
    BRAICH, TA
    GROGAN, TM
    HICKS, MJ
    GREENBERG, BR
    AMERICAN JOURNAL OF MEDICINE, 1986, 80 (02): : 304 - 306
12345