Therapeutic perspectives in Alzheimer's disease: research into slowing its progress

被引：0
|
作者：
Piau, A. [1 ]
Hein, C. [1 ]
Nourhashemi, F. [1 ,2 ]
Vellas, B. [1 ,2 ]
机构：
[1] CHU Toulouse, Gerontopole, F-31300 Toulouse, France
[2] Inserm U558, F-31000 Toulouse, France
来源：
CAHIERS DE L ANNEE GERONTOLOGIQUE | 2009年 / 1卷 / 01期
关键词：
Alzheimer's disease; Disease-modifying therapies; Research; Clinical trials;
D O I：
10.1007/s12612-009-0013-0
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Several agents have been approved for treating Alzheimer's Disease. Their effects are limited and they do not modify disease progression. Investigation into new approaches targeting the presumed underlying pathogenic mechanisms is a major focus of current research. Anti-amyloid agents are the main subjects of clinical investigation. Tau-related therapies and other alternative approaches are also under development as neuro-protective agents and neuro-restorative techniques. This article describes the various disease-modifying therapies currently under investigation.
引用
收藏
页码：15 / 25
页数：11
相关论文
共 50 条
  • [21] The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
    Swerdlow, Russell H.
    Burns, Jeffrey M.
    Khan, Shaharyar M.
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2014, 1842 (08): : 1219 - 1231
  • [22] Biofluid Biomarkers of Alzheimer’s Disease: Progress, Problems, and Perspectives
    Shan Huang
    Yan-Jiang Wang
    Junhong Guo
    [J]. Neuroscience Bulletin, 2022, 38 : 677 - 691
  • [23] Research progress on flavonoids on prevention of alzheimer's disease
    Huang, Juqing
    Zhang, Ying
    [J]. Journal of Chinese Institute of Food Science and Technology, 2014, 14 (02) : 193 - 200
  • [24] Progress in Alzheimer’s disease research in the last year
    Daniela Galimberti
    Elio Scarpini
    [J]. Journal of Neurology, 2013, 260 : 1936 - 1941
  • [25] Progress in Alzheimer's disease research in the last year
    Galimberti, Daniela
    Scarpini, Elio
    [J]. JOURNAL OF NEUROLOGY, 2013, 260 (07) : 1936 - 1941
  • [26] Research Progress of Nanocarriers for the Treatment of Alzheimer's Disease
    Li, Lili
    Zhang, Jiajia
    Huang, Xiaoyue
    Du, Jingguo
    Tu, Zhiqiang
    Wu, Haotian
    Liu, Xu
    Yuan, Mingqing
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2023, 29 (02) : 95 - 115
  • [27] Research Progress on the Regulation of Resveratrol on Alzheimer’s Disease
    Wu L.
    Zhang H.
    Wu T.
    Chen N.
    [J]. Shipin Kexue/Food Science, 2023, 44 (03): : 237 - 245
  • [28] Research Progress of Eye Movement Analyses and its Detection Algorithms in Alzheimer's Disease
    He, Xueying
    Selesnick, Ivan
    Zhu, Ming
    [J]. CURRENT ALZHEIMER RESEARCH, 2024, 21 (02) : 91 - 100
  • [29] Gut Microbiota and Alzheimer's Disease: Pathophysiology and Therapeutic Perspectives
    Li, Yanli
    Wang, Rui
    Li, Qian
    Wang, Yan-Jiang
    Guo, Junhong
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2021, 83 (03) : 963 - 976
  • [30] Antihypertensive medications ameliorate Alzheimer's disease pathology by slowing its propagation
    Affleck, Andrew J.
    Sachdev, Perminder S.
    Stevens, Julia
    Halliday, Glenda M.
    [J]. ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS, 2020, 6 (01)
12345