(8A-ALPHA,12A-ALPHA,13A-ALPHA)-5,8,8A,9,10,11,12,12A,13,13A-DECAHYDRO-3-METHOXY-12-(METHYLSULFONYL)-6H-ISOQUINO[2,1-G][1,6]NAPHTHYRIDINE, A POTENT AND HIGHLY SELECTIVE ALPHA2-ADRENOCEPTOR ANTAGONIST

被引：40

作者：

CLARK, RD ^{[1
]}

REPKE, DB ^{[1
]}

KILPATRICK, AT ^{[1
]}

BROWN, CM ^{[1
]}

MACKINNON, AC ^{[1
]}

CLAGUE, RU ^{[1
]}

SPEDDING, M ^{[1
]}

机构：

[1] SYNTEX RES CTR,DEPT PHARMACOL,EDINBURGH EH14 4AP,SCOTLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 09期

关键词：

D O I：

10.1021/jm00129a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2034 / 2036

页数：3

共 35 条

[31] CRYSTAL-STRUCTURE OF 2,8,14,20-TETRAMETHYLPENTACYCLO-[19.3.1.1(3,7).1(9,13).1(15,19)]OCTACOSA-1-(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-DODECAENE-4,6,10,12,16,18,22,24-OCTOL, C32H32O8
ZAHN, G
SIELER, J
MULLER, K
HENNIG, L
MANN, G
ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1994, 209 (05): : 468 - 469
[32] CRYSTAL-STRUCTURE OF 2,8,14,20-TETRAMETHYLPENTACYCLO-[19.3.1.1(3,7).1(9,13)1(15,19)]OCTACOSA-1-(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-DODECAENE-4,6,10,12,16,18,22,24-OCTAETHYL ETHER, C48H64O8
ZAHN, G
MULLER, K
MANN, G
ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1994, 209 (05): : 473 - 474
[33] Novel stereoselective syntheses of the fused benzazepine dopamine D1 antagonist (6aS,13bR)-11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol (Sch 39166):: 2.: L-homophenylalanine-based syntheses
Draper, RW
Hou, D
Iyer, R
Lee, GM
Liang, JT
Mas, JL
Vater, EJ
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 1998, 2 (03) : 186 - 193
[34] Novel stereoselective syntheses of the fused benzazepine dopamine D1 antagonist (6aS,13bR)-11-chloro-6,6a,7,8,9,13b-hexahydro-7-methy-5H-benzo[d]naphth[2,1-b]azepin-12-ol (Sch 39166):: 1.: Aziridinium salt based syntheses
Draper, RW
Hou, D
Iyer, R
Lee, GM
Liang, JT
Mas, JL
Tormos, W
Vater, EJ
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 1998, 2 (03) : 175 - 185
[35] THE CORRESPONDENCE OF OLDENBURG,HENRY, VOL 1, 1641-1662, VOL 2, 1663-1665, VOL 3, 1666-1667, VOL 4, 1667-1668, VOL 5, 1668-1669, VOL 6, 1669-1670, VOL 7, 1670-1671, VOL 8, 1671-1672, VOL 9, 1672-1673, VOL 10, JUNE 1673 APRIL 1674, VOL 11, MAY 1674 SEPTEMBER 1675, VOL 12, 1675-1676, VOL 13, 1676-1677 - ADDITIONS AND CORRECTIONS, VOL 1-11 - OLDENBURG,H,
SHAPIN, S
ISIS, 1987, 78 (293) : 417 - 424

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