QUANTITATIVE NONDESTRUCTIVE DETERMINATION OF SALICYLIC-ACID ACETATE IN ASPIRIN TABLETS BY RAMAN-SPECTROSCOPY

被引：29
|
作者：
KONTOYANNIS, CG [1 ]
ORKOULA, M [1 ]
机构：
[1] UNIV PATRAS,DEPT PHARM,GR-26500 PATRAI,GREECE
来源：
TALANTA | 1994年 / 41卷 / 11期
关键词：
D O I：
10.1016/0039-9140(94)00169-3
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Laser Raman spectroscopy was used for the quantitative determination of aspirin in aspirin-maize starch tablets. A calibration curve was constructed from spectra obtained from tablets with known quantities of aspirin and starch. The calibration curve is given from the relationship: I-552/I-478 = (W-aspirin/W-starch) x 4.21, where I-552 and I-478 and the relative Raman intensities for the 552 and 478 cm(-1) Raman shift, respectively. W-aspirin and W-starch represent the weight of aspirin and starch in a pellet.
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页码：1981 / 1984
页数：4
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