Synthesis, characterization and antimicrobial screening of novel substituted 5-oxo-imidazoline

4-N, N-dimethyl amino benzaldehyde condensed with hydrazine hydrate in methanol medium furnished N-amino-4-N, N-dimethyl amino phenyl azomethine (1a). Different aromatic aldehyde on treatment with benzoyl glycine in acetic unhydride and sodium acetate medium results 4-substituted benzylidin-2-phenyl-5-oxazolinones (2a-g). 4-substituted benzylidin-2-phenyl-5-oxazolinones (2a-g) on refluxing with N-amino-4-N, N-dimethyl amino phenyl azomethine (1a) in pyridine medium yields 1-(4'-N, N-dimethyl amino benzylidine amino)-2-phenyl-4-(substituted benzylidin)-5-oxo-imidazoline (3a-g). The newly synthesised compounds were characterized on the basis of elemental analysis and 1H NMR, IR spectral data. The synthesized compounds have been screened for their antimicrobial activity against gram +ve and gram -ve bacteria. Some of the products exhibited comparable activity with non standard drugs at same concentration.