RETINOBENZOIC ACIDS .4. CONFORMATION OF AROMATIC AMIDES WITH RETINOIDAL ACTIVITY - IMPORTANCE OF TRANS-AMIDE STRUCTURE FOR THE ACTIVITY

被引：84
|
作者：
KAGECHIKA, H [1 ]
HIMI, T [1 ]
KAWACHI, E [1 ]
SHUDO, K [1 ]
机构：
[1] UNIV TOKYO,FAC PHARMACEUT SCI,7-3-1 HONGO,BUNKYO KU,TOKYO 113,JAPAN
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 10期
关键词：
D O I：
10.1021/jm00130a011
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：2292 / 2296
页数：5
相关论文
共 34 条
  • [1] RETINOBENZOIC ACIDS .1. STRUCTURE-ACTIVITY-RELATIONSHIPS OF AROMATIC AMIDES WITH RETINOIDAL ACTIVITY
    KAGECHIKA, H
    KAWACHI, E
    HASHIMOTO, Y
    HIMI, T
    SHUDO, K
    JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (11) : 2182 - 2192
  • [2] RETINOIDAL DIENAMIDES AND RELATED AROMATIC AMIDES - REPLACEMENT OF THE 9-ENE STRUCTURE OF RETINOIC ACID WITH A TRANS-AMIDE OR CIS-AMIDE GROUP
    SHIMASAKI, H
    KAGECHIKA, H
    FUKASAWA, H
    KAWACHI, E
    SHUDO, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1995, 43 (01) : 100 - 107
  • [3] RETINOIDAL DIENAMIDES AND RELATED AROMATIC AMIDES - REPLACEMENT OF 9,10-DOUBLE BOND OF RETINOIC ACID WITH TRANS-AMIDE OR CIS-AMIDE GROUP
    SHIMASAKI, H
    KAGECHIKA, H
    FUKASAWA, H
    KAWACHI, E
    SHUDO, K
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 88 - MEDI
  • [4] RETINOBENZOIC ACIDS .3. STRUCTURE ACTIVITY RELATIONSHIPS OF RETINOIDAL AZOBENZENE-4-CARBOXYLIC ACIDS AND STILBENE-4-CARBOXYLIC ACIDS
    KAGECHIKA, H
    HIMI, T
    NAMIKAWA, K
    KAWACHI, E
    HASHIMOTO, Y
    SHUDO, K
    JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (05) : 1098 - 1108
  • [5] RETINOBENZOIC ACIDS .2. STRUCTURE ACTIVITY RELATIONSHIPS OF CHALCONE-4-CARBOXYLIC ACIDS AND FLAVONE-4'-CARBOXYLIC ACIDS
    KAGECHIKA, H
    KAWACHI, E
    HASHIMOTO, Y
    SHUDO, K
    JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (04) : 834 - 840
  • [6] Structure-activity study of retinoid agonists bearing substituted dicarba-closo-dodecaborane.: Relation between retinoidal activity and conformation of two aromatic nuclei
    Endo, Y
    Iijima, T
    Yaguchi, K
    Kawachi, E
    Inoue, N
    Kagechika, H
    Kubo, A
    Itai, A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (10) : 1307 - 1311
  • [7] STRUCTURE ACTIVITY RELATIONSHIP OF THE AROMATIC AMIDES OF N-SUBSTITUTED ALPHA-PIPERIDINECARBON ACIDS
    MARINOV, BS
    BERDYAEV, SY
    LEBEDEVA, AS
    LIKHOSHERSTOV, AM
    BIOLOGICHESKIE MEMBRANY, 1992, 9 (08): : 803 - 809
  • [8] OPTICALLY-ACTIVE AROMATIC-AMINO-ACIDS .4. SYNTHESIS AND ANALGESIC ACTIVITY OF 4 DERIVATIVES OF D-TYROSINE
    ARNOLD, ZS
    POLISH JOURNAL OF CHEMISTRY, 1985, 59 (7-9) : 837 - 843
  • [9] QUANTITATIVE STRUCTURE ACTIVITY STUDIES OF BENZOYLPHENYLUREA LARVICIDES .4. BENZOYL ORTHO SUBSTITUENT EFFECTS AND MOLECULAR-CONFORMATION
    SOTOMATSU, T
    NAKAGAWA, Y
    FUJITA, T
    PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 1987, 27 (02) : 156 - 164
  • [10] STRUCTURE-ACTIVITY RELATIONS .4. REACTIVITY AND ANTI-BACTERIAL ACTIVITY OF 3-AROYLACRYLIC ACIDS AND THEIR METHYL-ESTERS
    BOWDEN, K
    DIXON, MS
    RANSON, RJ
    JOURNAL OF CHEMICAL RESEARCH-S, 1979, (01): : 8 - &
1234