NEW SOLID-PHASE FOR AUTOMATED SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING AN AMINO-ALKYL LINKER AT THEIR 3'-END

被引:31
|
作者
ASSELINE, U
THUONG, NT
机构
[1] Centre de Biophysique Moléculaire, C.N.R.S., 1A, avenue de la Recherche Scientifique
关键词
D O I
10.1016/S0040-4039(00)94339-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Immobilization of an aliphatic amino-alcohol on a 2,2′-dithiodiethanol derivatized support via a carbamate linkage formation allows automated synthesis of oligonucleotides involving amino-alkyl derivatizations at their 3′-end. © 1990.
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页码:81 / 84
页数:4
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