Articular manifestations;
Lyme disease;
Differencial diagnosis;
Treatment and evolution;
D O I:
10.1016/j.reuma.2015.10.013
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objectives: To determine the percentage of Lyme patients with articular manifestations in NW Spain and to know their evolution and response to treatment. Patients: A retrospective study (2006-2013) was performed using medical histories of confirmed cases of Lyme disease showing articular manifestations. Clinical and laboratory characteristics, together with the treatment and evolution of the patients, were analysed. Results: Seventeen out of 108 LD confirmed patients (15.7%) showed articular manifestations. Regarding those 17 patients, 64.7%, 29.4% and 5.9% presented arthritis, arthralgia and bursitis, respectively. The knee was the most affected joint. Articular manifestations were often associated to neurological, dermatological and cardiac pathologies. Otherwise, most patients were in Stage III. The 11.8% of the cases progressed to a recurrent chronic arthritis despite the administration of an appropriate treatment. Conclusions: Lyme disease patients showing articular manifestations should be included in the diagnosis of articular affections in areas of high risk of hard tick bite, in order to establish a suitable and early treatment and to avoid sequels. (C) 2015 Elsevier Espana, S.L.U. and Sociedad Espanola de Reumatologla y Colegio Mexicano de Reumatologia. All rights reserved.
机构:
Hop Univ Paris Sud, Le Kremlin Bicetre, France
Univ Paris Sud, Rheumatol, Le Kremlin Bicetre, FranceHop Univ Paris Sud, Le Kremlin Bicetre, France
Dupre, Anastasia
Collins, Michael
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h-index: 0
机构:
Hop Univ Paris Sud, Le Kremlin Bicetre, France
Univ Paris Sud, Gastroenterol, Le Kremlin Bicetre, FranceHop Univ Paris Sud, Le Kremlin Bicetre, France
Collins, Michael
Carbonnel, Franck
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h-index: 0
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Hop Univ Paris Sud, Le Kremlin Bicetre, France
Univ Paris Sud, Gastroenterol, Le Kremlin Bicetre, FranceHop Univ Paris Sud, Le Kremlin Bicetre, France
Carbonnel, Franck
Mariette, Xavier
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h-index: 0
机构:
Hop Univ Paris Sud, AP HP, Rheumatol Dept, Ctr Immunol Viral Infect & Autoimmune Dis, Le Kremlin Bicetre, France
Univ Paris Sud, INSERM, Paris, France
Univ Paris Sud, Immunol Viral Infect & Autoimmune Dis, IDMIT, CEA,INSERM,U1184, Le Kremlin Bicetre, France
Univ Paris Sud, Immunol Viral Infect & Autoimmune Dis, IDMIT, CEA,INSERM,U1184, Fontenay Aux Roses, FranceHop Univ Paris Sud, Le Kremlin Bicetre, France
机构:
New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Nowakowski, John
McKenna, Donna
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h-index: 0
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New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
McKenna, Donna
Nadelman, Robert B.
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h-index: 0
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New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Nadelman, Robert B.
Bittker, Susan
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New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Bittker, Susan
Cooper, Denise
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New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Cooper, Denise
Pavia, Charles
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h-index: 0
机构:
New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
New York Inst Technol, New York Coll Osteopath Med, Dept Biomed Sci, Old Westbury, NY 11568 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Pavia, Charles
Holmgren, Diane
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h-index: 0
机构:
New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Holmgren, Diane
Visintainer, Paul
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h-index: 0
机构:
Baystate Hlth Syst, Div Acad Affairs, Springfield, MA USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
Visintainer, Paul
Wormser, Gary P.
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h-index: 0
机构:
New York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USANew York Med Coll, Div Infect Dis, Dept Med, Valhalla, NY 10595 USA
机构:
Univ Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, FranceUniv Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, France
Dupre, Anastasia
Collins, Michael
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris Saclay, Univ Paris Sud, Dept Gastroenterol, AP HP, Le Kremlin Bicetre, FranceUniv Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, France
Collins, Michael
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h-index:
机构:
Nocturne, Gaetane
Carbonnel, Franck
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris Saclay, Univ Paris Sud, Dept Gastroenterol, AP HP, Le Kremlin Bicetre, FranceUniv Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, France
Carbonnel, Franck
Mariette, Xavier
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, FranceUniv Paris Saclay, Dept Rheumatol, INSERM, Univ Paris Sud,AP HP,UMR1184, Le Kremlin Bicetre, France